Mechanistic Pathways Toward the Synthesis of Heterocycles Under Cross-Dehydrogenative Conditions



Due to the richness of the field of cross-dehydrogenative coupling reactions and the plethora of applications toward the synthesis and derivatization of heterocyclic molecules, there is an increasing amount of synthetic methodologies which spread across different catalytic fields and hence, yield to a huge variety of operating mechanisms. Although all the pathways follow the same underlying principles, they can be easily differentiated according to the type of activation (thermal of photocatalyzed) and the type of catalyst (metallic or metal-free). In this account, we have summarized the most recent and relevant examples under the aforementioned categories, focusing especially on those presenting the most compelling and better understood mechanisms.


Reaction mechanisms Heterocycles Organometallic catalysis Oxidative coupling Photocatalysis 


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  1. 1.Leibniz Institute for Catalysis (LIKAT)RostockGermany

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