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Release of Cytokine and Its Control During the Formation of Psoariasis

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Mathematical Models for Therapeutic Approaches to Control Psoriasis

Part of the book series: SpringerBriefs in Applied Sciences and Technology ((BRIEFSMATHMETH))

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Abstract

It is a well-known reality that during the interaction between T-Cells and Keratinocytes, cytokines are released. As a result, T-Cell population is reduced. These cytokines are transformed into Keratinocytes in the course of some cell-biological mechanisms and it facilitates the generation of the growth of Keratinocytes, which in turn originates into the disease Psoriasis. In our basic model of Psoriasis discussed earlier, there is no such conception of cytokines release during the interaction of T-Cells and Keratinocytes. Actually, the generation of the disease Psoriasis in the context of cytokines release is not yet been properly explored. Here, our aim is to analyze the Psoriatic system in the presence of cytokines release, which in turn generates Keratinocytes and also to control the over production of Keratinocytes to keep the disease under control.

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Correspondence to Priti Kumar Roy .

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Roy, P.K., Datta, A. (2019). Release of Cytokine and Its Control During the Formation of Psoariasis. In: Mathematical Models for Therapeutic Approaches to Control Psoriasis. SpringerBriefs in Applied Sciences and Technology(). Springer, Singapore. https://doi.org/10.1007/978-981-13-9020-3_3

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