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Trends in Research and Development of Phenolic Phytochemicals as Potential Antidiabetic Therapeutics

  • Muddasarul Hoda
  • Shanmugam Hemaiswarya
  • Mukesh Doble
Chapter

Abstract

Phenolic phytochemicals are currently used as dietary supplements in preventative and complementary medicine. Couple of decades ago, there was limited scientific knowledge concerning its pharmacology and therapeutic mode of action. In subsequent years, emphasis is being given in the form of project grants and elaborate research and developments in major domains of phytotherapeutics such as bioavailability, toxicity, molecular mechanisms of actions, isolation, and characterization of new phenolic compounds. However, exhaustive efforts have been made to produce reproducible data for randomized clinical trials. A number of web-platforms such as CONSORT, CARDS database, and clinicaltrials.gov are at the center stage of regulating and monitoring progress in research and development of phytophenolic compounds as potential antidiabetic therapeutics. Novel identification and extraction methods are being explored for the isolation of novel analogs of prominent phenolic compounds from plants. This chapter emphasizes on the current issues and future prospects of therapeutic research of phytophenolic compounds.

Keywords

Phenolic phytochemicals CONSORT CARDS database Diabetes management 

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Muddasarul Hoda
    • 1
    • 2
  • Shanmugam Hemaiswarya
    • 1
  • Mukesh Doble
    • 1
  1. 1.Department of BiotechnologyIndian Institute of Technology MadrasChennaiIndia
  2. 2.Department of Biological SciencesAliah UniversityKolkataIndia

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