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Marine-Derived Biomaterials for Tissue Engineering Applications pp 1–25Cite as

Thoughts and Tribulations on Bioceramics and Marine Structures

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Part of the book series: Springer Series in Biomaterials Science and Engineering ((SSBSE,volume 14))

Abstract

Marine organisms are structured and constituted by materials with a vast range of properties and characteristics that may justify their potential application within the biomedical field. This is demonstrated by the biological effectiveness of marine structures such as corals and shells and sponge skeletons to house self-sustaining musculoskeletal tissues and their ability to promote bone formation though the use of extracts from sponging and nacre seashells. The design and composition of marine structures have been instrumental in the solving vital problems in regenerative medicine through the introduction of basic remedies that provides frameworks and highly accessible sources of osteopromotive analogues of bioceramic monoliths, nanofibres, micro and macrospheres. The clinical success of any future regenerative implants will be dependent on the production of highly proficient scaffolds that biologically operates at the nano-, micro- and macroscopic levels. Moreover, the implant will also need to coordinate, assemble, and organize cells into tissues as well as releasing encapsulated chemical signals in a targeted way and convey them into the body. As a result, an increasing number of different types of compounds are being isolated from aquatic organisms and transformed into products for health applications, including controlled drug delivery and tissue engineering devices. Despite the fact that they are extremely effective, the development of these materials has their drawbacks that needs be addressed. This chapter reviews the current bioceramics and natural marine structures including their structure, morphology, and applications in regenerative medicine, bone grafts, and drug delivery. In addition, the extraction of biological materials such as proteins from marine materials will also be discussed. An example of this specific biomimicry is provided by filtering the microskeleton of Foraminifera and coralline microspheres. New selected strategies based on our research as well as the works of others concerning the engineering of new bone tissues based on biomimicry will be also examined.

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Author information

Authors and Affiliations

  1. School of Life Sciences, Biomaterials and Advanced Tissue Engineering, University of Technology Sydney, GPO BOX 123, Broadway, Sydney, NSW, 2007, Australia

    Besim Ben-Nissan, Andy H. Choi, David W. Green & Ipek Karacan

  2. Department of Physiology, Cerrahpasa Medical Faculty, University of Istanbul, Cerrahpasa, 34099, Istanbul, Turkey

    Sibel Akyol

  3. Laboratoire CIRIMAT, UMR 5085 UPS-INPT-CNRS, 35 chemin des maraichers, 31062, Toulouse Cedex 09, France

    Sophie Cazalbou

Authors
  1. Besim Ben-Nissan
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  2. Andy H. Choi
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  3. David W. Green
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  4. Ipek Karacan
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  5. Sibel Akyol
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  6. Sophie Cazalbou
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Correspondence to Besim Ben-Nissan .

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Editors and Affiliations

  1. School of Mathematical and Physical Sciences, University of Technology Sydney, Sydney, NSW, Australia

    Andy H. Choi

  2. Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia

    Besim Ben-Nissan

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Ben-Nissan, B., Choi, A.H., Green, D.W., Karacan, I., Akyol, S., Cazalbou, S. (2019). Thoughts and Tribulations on Bioceramics and Marine Structures. In: Choi, A., Ben-Nissan, B. (eds) Marine-Derived Biomaterials for Tissue Engineering Applications. Springer Series in Biomaterials Science and Engineering, vol 14. Springer, Singapore. https://doi.org/10.1007/978-981-13-8855-2_1

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