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Applications of Emerging Memory Technology pp 133–157Cite as

Memristive Biosensors for Ultrasensitive Diagnostics and Therapeutics

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Part of the book series: Springer Series in Advanced Microelectronics ((MICROELECTR.,volume 63))

Abstract

The coupling of memristive effect with biological interactions results in innovative nanobiosensors with high performance in both diagnostics and therapeutics. Silicon nanowire arrays exhibiting a memristive electrical response are acquired through a top-down nanofabrication process. Surface treatments implementing sophisticated bio-functionalization strategies and adopting suitably selected biological materials give rise to the memristive biosensors. The particular electrical response of these novel biosensors leverages the modification of the hysteretic properties exhibited by the memristive effect before and after the bio-modification, to achieve an efficient detection of biological processes. Memristive biosensors successfully address the issue of the early detection of cancer biomarkers providing a new technology for high performance, ultrasensitive, label-free electrochemical sensing platforms. They also offer the capability of detecting extremely small traces of cancer biomarkers, as well as effective screening and continuous monitoring of therapeutic compounds in full human serum bringing novelty and solutions in the medical practice, especially in the field of personalized medicine.

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Notes

  1. 1.

    Source of original text [3].

  2. 2.

    Source of original text [3, 33].

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Authors and Affiliations

  1. Integrated Systems Laboratory, EPFL, Lausanne, Switzerland

    Ioulia Tzouvadaki, Giovanni De Micheli & Sandro Carrara

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  1. Ioulia Tzouvadaki
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  2. Giovanni De Micheli
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  3. Sandro Carrara
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Correspondence to Ioulia Tzouvadaki .

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Editors and Affiliations

  1. Department of Electrical Engineering, Indian Institute of Technology Delhi, New Delhi, Delhi, India

    Manan Suri

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Tzouvadaki, I., De Micheli, G., Carrara, S. (2020). Memristive Biosensors for Ultrasensitive Diagnostics and Therapeutics. In: Suri, M. (eds) Applications of Emerging Memory Technology. Springer Series in Advanced Microelectronics, vol 63. Springer, Singapore. https://doi.org/10.1007/978-981-13-8379-3_5

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  • DOI: https://doi.org/10.1007/978-981-13-8379-3_5

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