Functionalized Silk for Surgical Suture Applications
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In the present state of environmental consciousness, the modern quality necessities of a product not only stress on the inherent functionality but also a preparation method that is ecological. Hence, investigations on coating agents based on natural extracts for medical and healthcare textiles application are gaining global attention. In this work, a novel attempt has been made to coat the silk sutures with natural bioactive agents such as aloe vera, curcumin, and chitosan. The exhaustion method was adopted for the application of extracts in two different combinations, aloe vera, curcumin, and aloe vera, curcumin in combination with chitosan. Suture properties such as tenacity, knot strength, coefficient of friction, and antimicrobial property were tested. The process variables such as time, temperature, and concentration were optimized for better performance of the sutures by adopting the Box–Behnken response surface methodology. Sutures treated with aloe vera and curcumin in combination with chitosan had low values of coefficient of friction, i.e., 0.199 and maximum values of tenacity and knot strength of 39.86cN/tex and 30.56 cN/tex, respectively. The silk sutures treated with aloe vera and curcumin in combination with chitosan, under the optimized conditions exhibited a zone of inhibition of 6 mm for Staphylococcus aureus and 4 mm for Escherichia coli bacteria.
KeywordsSilk Suture Tenacity
One of the author Dr. S. Viju has been granted Career Award for Young Teachers (CAYT) by All India Council for Technical Education (AICTE), Government of India under Project Number [F.No.11-36/RIFD/CAYT/POL-1/2014-15]. The financial support received from AICTE for carrying out this work is gratefully acknowledged.
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