Insulin Pharmacodynamics, Pharmacokinetics, and Insulin Regimens

  • Sanjeev Kelkar
  • Shubhangi Muley
  • Prakash Ambardekar


Pharmacodynamics is the action the drug has on the body. The main elements connected with it are the plasma concentration, protein binding, and the receptor affinity. Half-life in plasma is the duration in which the drug level falls to 50%. Pharmacokinetics is how the drug travels in the body over time and their variations in concentration across time in blood. So far we have dealt with considerable details both these aspects of insulin in the body tissues and cells. Here these functions will be more fully understood against the backdrop of pharmacotherapy of insulin and its pharmacokinetics from a different perspective in all kinds of situations in diabetes.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Sanjeev Kelkar
    • 1
  • Shubhangi Muley
    • 2
  • Prakash Ambardekar
    • 3
  1. 1.Private PracticePuneIndia
  2. 2.Senior Consultant AnesthesiologistCentral India Institute of Medical ScienceNagpurIndia
  3. 3.Consultant, AnesthesioligistFortis S L Raheja HospitalMumbaiIndia

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