Physiology of Insulin

  • Sanjeev Kelkar
  • Shubhangi Muley
  • Prakash Ambardekar


It is important to understand the insulin physiology, to comprehend in full the changes that occur in insulin deficiency state, and to facilitate the attempts to bring up the insulin levels to an effective state. In particular the differences in the metabolism between the portal insulin levels and the pharmacodynamics of the exogenously administered insulin should also be understood. In the same section, we will also describe some nonmetabolic actions of insulin underscoring the significance of insulin. Unless these actions and the scope of insulin physiology are precisely understood, the insulin and diabetes management will become a mechanistic unintelligent centered only on glucose control. Sadly this is the state of care in this area across the subcontinent and possibly other less developed countries as well.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Sanjeev Kelkar
    • 1
  • Shubhangi Muley
    • 2
  • Prakash Ambardekar
    • 3
  1. 1.Private PracticePuneIndia
  2. 2.Senior Consultant AnesthesiologistCentral India Institute of Medical ScienceNagpurIndia
  3. 3.Consultant, AnesthesioligistFortis S L Raheja HospitalMumbaiIndia

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