Skip to main content

Recent Patents on Endophytic Fungi and Their International Market

  • Chapter
  • First Online:

Abstract

An endophytic fungus is a very great microbe that can grow in all parts of plant, root, stem, leaf, and fruit. These fungi are alive inside the plant as symbiosis or mutualism. Through the life cycle of this type of fungi inside plant is coming from secreting secondary metabolite compounds that possible utilizing for plant and other fields. Many of these compounds can be a novel product. Therefore, this chapter offers the patents recently to show its importance for plants, industry, medicine, and ecosystem. Patents showed some of the novel isolates as genera Neotyphodium sp., Muscodor sp., Curvularia sp., and Fusarium sp. Also, many natural compounds were discovered as pyrrolizidine alkaloid, pericoannosin A, praeruptorin C, cytosporaphenone A, etc. There are many companies using these patents prepared in special formula to sell in international markets. This possibility is helpful to enhance the resistance of plants and humans from diseases without occurrence of any collateral damages. The international markets and research centers work together with patent may bring several new products of new strains or isolates and also new secondary metabolites of endophytic fungi to the markets. That can utilizing in different industries like as biopesticdes, and others that useful and to get the consumer confidence.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Al-Ani LKT (2006) Induce resistance against Cucumber mosaic virus by Pseudomonas fluorescens Migula. M.Sc., Department of Plant Protection, College of Agriculture, University of Baghdad, Baghdad, Iraq.p 90

    Google Scholar 

  • Al-Ani LKT (2010) Biological control of Fusarium wilt of banana by non pathogenic Fusarium oxysporum. PPSKH colloquium, Pust Pengajian Sains Kajihayat/School of Biological Sciences, USM, June, p 10

    Google Scholar 

  • Al-Ani LKT (2017a) PGPR: agood step to control several of plant pathogens. In: Singh HB, Sarma BK, Keswani C (eds) Advances in PGPR research. CABI, UK, pp 398–410

    Chapter  Google Scholar 

  • Al-Ani LKT (2017b) Potential of utilizing biological and chemical agents in the control of Fusarium wilt of banana. PhD, School of Biology Science, Universiti Sains Malaysia, Pulau Pinang, Malaysia.p 259

    Google Scholar 

  • Al-Ani LKT (2018a) Trichoderma: beneficial role in sustainable agriculture by plant disease management. In: Egamberdieva D, Ahmad P (eds) Plant microbiome: stress response. Microorganisms for sustainability, vol 5. Springer, Singapore, pp 105–126

    Chapter  Google Scholar 

  • Al-Ani LKT (2018b) Trichoderma from extreme environments: physiology, diversity, and antagonistic activity. In: Egamberdieva D, Birkeland N-K, Panosyan H, Li W-J (eds) Extremophiles in Eurasian ecosystems: ecology, diversity, and applications. Microorganisms for sustainability, vol 8. Springer, Singapore, pp 388–403

    Google Scholar 

  • Al-Ani LKT (2019a) Secondary metabolites of nonpathogenic Fusarium spp.; scope in agriculture. In: Singh HB, Keswani C, Reddy MS, Royano ES, García-Estrada C (eds) Secondary metabolites of plant growth promoting rhizomicroorganisms - discovery and applications. Springer, Singapore, pp 59–76

    Chapter  Google Scholar 

  • Al-Ani LKT (2019b) Bioactive secondary metabolites of Trichoderma spp. for efficient management of phytopathogens. In: Singh HB, Keswani C, Reddy MS, Royano ES, García-Estrada C (eds) Secondary metabolites of plant growth promoting rhizomicroorganisms - discovery and applications. Springer, Singapore, pp 125–143

    Chapter  Google Scholar 

  • Al-Ani RA, Al-Ani LKT (2011) Induced of systemic resistance in cucumber plants against Cucumber mosaic virus (CMV) by Pseudomonas fluorescens Migula. Arab J Plant Protect 29:36–42

    Google Scholar 

  • Al-Ani LKT, Albaayit SFA (2018a) Antagonistic of some Trichoderma against Fusarium oxysporum sp. f. cubense tropical race 4 (FocTR4). International conference on Research in Education & Science, ICRES April 28 – May 1, Marmaris, Turkey, pp. 271 (Abstract)

    Google Scholar 

  • Al-Ani LKT, Albaayit SFA (2018b) Antagonistic of some Trichoderma against Fusarium oxysporum sp. f. cubense tropical race 4 (FocTR4). The Eurasia Proceedings of Science, Technology, Engineering & Mathematics (EPSTEM) 2:35–38

    Google Scholar 

  • Al-Ani LKT, Salleh B, Ghazali AHA (2013a) Biocontrol of Fusarium wilt of banana by Trichoderma spp. 8th PPSKH colloquium, Pust Pengajian Sains Kajihayat/School of Biological Sciences, USM, June 5–6

    Google Scholar 

  • Al-Ani LKT, Salleh B, Mohammed AM, Ghazali AHA, Al-Shahwany AW, Azuddin NF (2013b) Biocontrol of Fusarium wilt of banana by non-pathogenic Fusarium spp. International symposium on tropical fungi, ISTF, IPB International Convention Center, Bogor, Indonesia; 09/2013. p 50–51

    Google Scholar 

  • Al-Ani LKT, Yonus MI, Mahdii BA, Omer MA, Taher JK, Albaayit SFA, Al-Khoja SB (2018) First record of use Fusarium proliferatum fungi in direct treatment to control the adult of wheat flour Tribolium confusum, as well as, use the entomopathogenic fungi Beauveria bassiana. Ecology, Environment and Conservation 24(3):29–34

    Google Scholar 

  • Andrés MF, Diaz CE, Giménez C, Cabrera R, González-Coloma A (2017) Endophytic fungi as novel sources of biopesticides: the Macaronesian Laurel forest, a case study. Phytochem Rev:1–14

    Google Scholar 

  • Attitalla IH, Mansour SE, Mohamed WS, Al-Ani LKT, Mohammed AM, Faturi MY, Balal IAA, El-Maraghy SSM (2010a) Influence of Aspergillus Flavus and Aspergillus Terreus on the protein value of the two varieties of peanut grains. International conference, International Mycotoxin Conference, MycoRed, Penang –Malaysia, 1–4 Dec., (177)

    Google Scholar 

  • Attitalla IH, Laith KTA-A, Nasib MA, Balal IAA, Zakaria M, El-Maraghy SSM, Karim SMR (2010b) Screening of Fungi Associated With Commercial Grains and Animal Feeds in Al-Bayda Governorate, Libya. World Applied Sciences Journal 9(7):746–756

    Google Scholar 

  • Avanex Brochure (2017) Breakthrough technology bird deterrent grasses. Avanex® Unique Endophyte Technology.p 1–2. Online, website: http://www.pennington.com

  • Bacon CW, Hinton DM (1996) Symptomless endophytic colonization of maize by Fusarium moniliforme. Can J Bot 74:144–148

    Article  Google Scholar 

  • Bacon CW, Yates IE, Hinton DM, Meredith F (2001) Biological control of Fusarium moniliforme in maize. Environ Health Perspect 109(Suppl (2)):325–332

    CAS  PubMed  PubMed Central  Google Scholar 

  • Bin C, Lan L, Siping J, Jiayi X, Aiguo X, Dorje P, Jing L (2017) Application of the fungus and production pyrrocidines DH24 compound within a green flower meconopsis. CN Patent, CN106701594A

    Google Scholar 

  • Brown RS (2010) Texas foundation seed service – a production and commercialization unit for Texas AgriLife Research. Proceedings of the Seventh International Herbage Seed Conference Dallas, Texas USA, 11–13. Apr 2010, p 16–19

    Google Scholar 

  • Brown WG (2016) Clonostachys rosea inoculated plant materials with fungicides and adjuvants. WO Patent, WO2016011057A1

    Google Scholar 

  • Butler MS (2005) Natural products to drugs: natural product derived compounds in clinical trials. Nat Prod Rep 22:162–195

    Article  CAS  Google Scholar 

  • Changlun S, Shao C, Changyun W, Wang C, Xiaofeng M, Mu X, Rufang X, Xu R (2017) Alkaloid compound, preparation method thereof and use thereof as antiviral agent against herpes simplex virus type 1. WO Patent, WO2017036128A1

    Google Scholar 

  • Craven K (2010) Grass fungal endophytes and uses thereof. US Patent, US2012/0144533A1

    Google Scholar 

  • Demarest E (2015) How adaptive symbiotic technologies is using fungi to boost crop yields during drought. Online, website: https://agfundernews.com/how-adaptive-symbiotic-technologies-is-using-fungi-to-boost-yields-during-drought.html

  • Di ZH (2017) A pharmaceutical composition comprising for the treatment of chronic nephritis Penibruguieramine A, CN Patent, CN106389425A

    Google Scholar 

  • Di ZH, Deshun L (2017) A method of treating acute cerebral infarction pharmaceutical compositions. CN Patent, CN106551928A

    Google Scholar 

  • Dissanayakea RK, Ratnaweera PB, Williams DE, Wijayarathnea CD, Wijesundera RLC, Andersen RJ, de Silvaa ED (2016) Antimicrobial activities of endophytic fungi of the Sri Lankan aquatic plant Nymphaea nouchali and chaetoglobosin A and C, produced by the endophytic fungus Chaetomium globosum. Mycology 7(1):1–8

    Article  Google Scholar 

  • El-Maghraby OMO, Shebany YM (2014) Detection of mycotoxin produce by endophytic fungi. Int J Life Sci Res 2(4):37–42

    Google Scholar 

  • Ezra D, Liarzi O, Elad Y, Lousky T, Brown MS, Bucki P, Gamliel A, Lichter A, Dombrovsky A (2016) Uses of daldinia sp. or volatile organic compounds derived therefrom. WO Patent, WO2016125153A1

    Google Scholar 

  • Gandhi NR, Skebba VP, Strobel GA (2017) Antimicrobial compositions and related methods of use. US Patent, US9706773B2

    Google Scholar 

  • Gange AC, Eschen R, Wearn JA, Thawer A, Sutton BC (2011) Differential effects of foliar endophytic fungi on insect herbivores attacking a herbaceous plant. Oecologia 168(4):1023–1031

    Article  Google Scholar 

  • González CA, Andres YMF, Diaz HCE, Reina AM, Lacret PR, Cabrera PA, Gimenez MC, Kaushik N (2017) Natural borad-spectrum biocides. WO Patent, WO2017068223A1

    Google Scholar 

  • Green WA, Herrgard MJ, Kerovuo JS, Lomelin D, Mathur EJ, Richarson TH, Schwartz AS, Strobel GA (2010). Endophytic fungus and uses therefore. WO Patent, WO2010115156A2

    Google Scholar 

  • Green WA, Herrgard MJ, Kerovuo JS, Lomelin D, Mathur EJ, Richardson TH, Schwartz AS, Strobel GA (2011) Endophytic fungus and uses therefore. US Patent, US2011/0182862Al

    Google Scholar 

  • Guan WQ, Haohua L, Lei W, Weimin Z, Qing C, Xiaoxia H (2012) Method for manually inducing Aquilaria sinensis to generate agilawood. CN Patent, CN102302041A

    Google Scholar 

  • Hamilton CE (2014) Expanding commercialization of mutualistic symbionts to increase biofeedstock production: symbiosis biofeedstock conference report. pp 39.Online, website: https://energy.gov/eere/bioenergy/downloads/symbiosis-biofeedstock-conference-expanding-commercialization-mutualistic

  • Henson JM, Sheehan KB, Rodriguez RJ, Redman RS (2007) Use of endophytic fungi to treat plants. US Patent, US7232565B2

    Google Scholar 

  • Henson JM, Sheehan KB, Rodriguez RJ, Redman RS (2011a) Curvularia strains and their use to confer stress tolerance and/or growth enhancement in plants. US Patent, US7906313B2

    Google Scholar 

  • Henson JM, Sheehan KB, Rodriguez RJ, Redman RS (2011b) Curvularia strains and their use to confer stress tolerance and/or growth enhancement in plants. US Patent, US2011/0183846A1

    Google Scholar 

  • Henson JM, Sheehan KB, Rodriguez RJ, Redman RS (2013) Methods of using Curvularia strains to confer stress tolerance and/or growth enhancement in plants. US Patent, US8524224B2

    Google Scholar 

  • Hiruma K, Gerlach N, Sacristán S, Nakano RT, Hacquard S, Kracher B, Neumann U, Ramírez D, Bucher M, O’Connell RJ, Schulze-Lefert P (2016) Root endophyte Colletotrichum tofieldiae confers plant fitness benefits that are phosphate status dependent. Cell 165(2):464–474

    Article  CAS  Google Scholar 

  • Hong L, Haibo T, Weimin Z, Yuan L, Yuchan C, Haohua L, Hua SZ (2017) Compound cytosporaphenone A preparation method and in the preparation of antineoplastic. CN Patent, CN106631775A

    Google Scholar 

  • Hume DE, Johnson RD, Simpson WR, Card SD (2014) Improved fungal endophytes. WO Patent, WO2014136070A1

    Google Scholar 

  • Hume, D.E., Johnson, R.D., Simpson, W.R., Card, S.D. (2016) Improved fungal endophytes. US Patent, US20160262335A1

    Google Scholar 

  • Idris AS, Nur RR, Ahmad TD, Madihah AZ, Tony PSH (2015) A composition to biologically control ganoderma disease and method of making thereof. WO Patent, WO2015170961A1

    Google Scholar 

  • Jacobson KL, William T, Hobbs TW, Balaban LA (2017).Incorporation of biological agents in fertilizers. US Patent, US20170197890A1

    Google Scholar 

  • Jian CC, Ping QL, Xin D, Lee SC, Ting H, Qiaoyan Z, Yiping J, Min J (2017) Salvia endophyte for improving productivity and its application and its active ingredient content. CN Patent, CN106801014A

    Google Scholar 

  • Jincheng L, Guodong Y, Yan W, Jianhua W, Fruit GX (2012) One kind of loco endophytic fungi Swainsonine method of detecting the content of. CN Patent, CN102590378A

    Google Scholar 

  • Johnson LJ, de Bonth ACM, Briggs LR, Caradus JR, Finch SC, Fleetwood DJ, Fletcher LR, Hume DE, Johnson RD, Popay AJ, Tapper BA, Simpson WR, Voisey CR, Card SD (2013) The exploitation of epichloae endophytes for agricultural benefit. Fungal Divers 60:171–188

    Article  Google Scholar 

  • Jones N (2013) Food fuelled with fungi, ecologists are starting to appreciate the power of microbes to make crops hardier. Nature.News. Online, Website:http://www.nature.com/news/food-fuelled-with-fungi-1.14339

  • Keswani C, Bisen K, Singh V, Sarma BK, Singh HB (2016) Formulation technology of biocontrol agents: present status and future prospects. In: Arora NK, Mehnaz S, Balestrini R (eds) Bioformulations for sustainable agriculture. Springer, New Delhi, pp 35–52

    Google Scholar 

  • Khan AR, Ullah I, Waqas M, Shahzad R, Hong SJ, Park GS, Jung BK, Lee IJ, Shin JH (2015) Plant growth-promoting potential of endophytic fungi isolated from Solanum nigrum leaves. World J Microbiol Biotechnol 31(9):1461–1466

    Article  CAS  Google Scholar 

  • Kharwar RN, Verma SK, Mishra A, Gond SK, Sharma VK, Afreen T, Kumar A (2011) Assessment of diversity, distribution and antibacterial activity of endophytic fungi isolated from a medicinal plant Adenocalymma alliaceum Miers. Symbiosis 55:39–46

    Article  Google Scholar 

  • Kwaśna H, Szewczyk W, Behnke-Borowczyk J (2016) Fungal root endophytes of Quercus robur subjected to flooding. For Pathol 46(1):35–46

    Article  Google Scholar 

  • Lam KS (2007) New aspects of natural products in drug discovery. Trends Microbiol 15:279–289

    Article  CAS  Google Scholar 

  • Lugtenberg BJJ, Caradus JR, Johnson LJ (2016) Fungal endophytes for sustainable crop production. FEMS Microbiol Ecol 92(12):1–17

    Article  Google Scholar 

  • Malcolm GM, Kuldau GA, Gugino BK, Jiménez-Gasco Mdel M (2013) Hidden host plant associations of soil borne fungal pathogens: an ecological perspective. Phytopathology 103(6):538–544

    Article  CAS  Google Scholar 

  • Malusá E, Vassilev N (2014) A contribution to set a legal framework for biofertilizers. Appl Microbiol Biotechnol 98:6599–6607

    Article  Google Scholar 

  • Mann R, Mattner S, Rochfort SJ, Sawbridge TI, Spangenberg GC (2012) Fungi and products thereof. WO Patent, WO2012159161A1

    Google Scholar 

  • Mohammed AM, Al-Ani LKT, Bekbayeva L, Salleh B (2011) Biological control of Fusarium oxysporum f. sp. cubense by Pseudomonas fluorescens and BABA in vitro. World Appl Sci J 15(2):189–191

    CAS  Google Scholar 

  • Mohammed AM, Al-Ani LKT, Salleh B (2013) Potential management of Fusarium oxysporum f. sp. cubense, the banana wilt pathogen by using Pseudomonas and beta-amino-butyric acid (BABA). International symposium on tropical fungi, ISTF, IPB International Convention Center, Bogor, Indonesia; 09/2013, p37

    Google Scholar 

  • Owen NL, Hundley N (2004) Endophytes—the chemical synthesizers inside plants. Sci Prog 87(2):79–99

    Article  CAS  Google Scholar 

  • Palencia ER, Hinton DM, Bacon CW (2010) The black aspergillus species of maize and peanuts and their potential for mycotoxin production. Toxins 2:399–416

    Article  CAS  Google Scholar 

  • Porras-Alfaro A, Bayman P (2010) Hidden fungi, emergent properties: endophytes and microbiomes. Annu Rev Phytopathol 49:291–315

    Article  Google Scholar 

  • Puri SC, Verma V, Amna T, Handa G, Gupta V, Verma N, Khajuria RK, Saxena AK, Qazi GN, Spitller M (2010) A novel endophytic camptothecin and camptothecinoid producing fungus and process of producing the same. EP Patent, EP1828374B1

    Google Scholar 

  • Ray S, Singh V, Bisen K, Keswani C, Singh S, Singh HB (2017) Endophytomicrobiont: a multifaceted beneficial interaction. In: Singh HB, Sarma BK, Keswani C (eds) Advances in PGPR research. CABI, UK, pp 218–233

    Google Scholar 

  • Redman RS, Rodriguez RJ (2010) Fungal isolates and their use to confer salinity and drought tolerance in plants. US Patent, US20100227357A1

    Google Scholar 

  • Rollando R, Aditya M, Notario D, Monica E, Sitepu R (2017) Kajian aktivitas antibakteri, antioksidan, dan sitotoksik fungi endofit genus Fusarium sp. isolat daun meniran (Phyllantus niruri Linn.). Pharmaciana 7(1):95–104

    Article  Google Scholar 

  • Rolshausen P, Roper MC (2017) Fungi antagonistic to Xylella fastidiosa. US Patent, US20170181440A1

    Google Scholar 

  • Singh HB, Sarma BK, Keswani C (2017) Advances in PGPR. CABI, UK

    Book  Google Scholar 

  • Spangenberg G, Guthridge KM, Forster JW, Sawbridge TI, Ludlow EJI, Kaur J, Rochfort SJ, Rabinovich MA, Ekanayake P (2016) Endophytes and related methods. EP Patent, EP2521442B1

    Google Scholar 

  • Spangenberg GC, Guthridge KM, Mann R, Sawbridge TI, Hettiarachchige IK, Ekanayake PN, Brohier ND, Rochfort SJ, Edwards J (2017) Brachiaria endophytes and related methods. WO Patent, WO2017049352A1

    Google Scholar 

  • Stamets PE (2008) Living systems from cardboard packaging materials. US Patent, US20080046277A1

    Google Scholar 

  • Stewart JF, Brown WG (2016) The production and use of endophytes as novel inoculants for promoting enhanced plant vigor, health, growth, yield reducing environmental stress and for reducing dependency on chemical pesticides for pest control. EP Patent, EP2001821B1

    Google Scholar 

  • Strobel GA (2003) Endophytes as sources of bioactive products. Microbes Infect 5(6):535–544

    Article  CAS  Google Scholar 

  • Strobel GA, Daisy B (2003) Bioprospecting for microbial endophytes and their natural products. Microbiol Mol Biol Rev 67:491–502

    Article  CAS  Google Scholar 

  • Strobel GA, Tomsheck AR (2013) System and method of producing volatile organic compounds from fungi. US Patent, US8501458B2

    Google Scholar 

  • Strobel G, Ford E, Harper JH (2007) Pestalotiopsis microsporia isolates and compounds derived therefrom. US Patent, US7192939B2

    Google Scholar 

  • Strobel G, Manker DC, Mercier J (2010a) Endophytic fungi and methods of use. US Patent, US7754203B2

    Google Scholar 

  • Strobel GA, Manker DC, Mercier J (2010b) Novel endophytic fungi and methods of use. EP patent, EP1379126B9

    Google Scholar 

  • Strobel G, Manker DC, Mercier J (2012a) Endophytic fungi and methods of use. US Patent, US8093024B2

    Google Scholar 

  • Strobel G, Manker DC, Mercier J (2012b) Endophytic fungi and methods of use. US Patent, US2012/0114610A1

    Google Scholar 

  • Sword GA (2016) Fungal endophytes for improved crop yields and protection from pests. US Patent, US9277751B2

    Google Scholar 

  • Sword GA (2017) Fungal endophytes for improved crop yields and protection from pests. US Patent, US9545111B2

    Google Scholar 

  • Taj G, Meena PD, Giri P, Pandey D, Kumar A, Kumar A (2015) Pathogenesis mechanisms employed by Alternaria species. J Oilseed Brassica 6(2):213–240

    Google Scholar 

  • Tapper BA, Cooper BM, Easton HS, Fletcher LR, Hume DE, Lane GA, Latch GCM, Pennell CGL, Popay AJ, Christensen MJ (2013) Method for protecting grass using an endophyte. EP Patent, EP2636302A1

    Google Scholar 

  • Teles HL, Silva GH, Castro-Gamboa I, Bolzani VDS, Pereira JO, Costa-Neto CM, Haddad R, Eberlin MN, Young MCM, Araújo AR (2005) Benzopyrans from Curvularia sp., an endophytic fungus associated with Ocotea corymbosa (Lauraceae). Phytochemistry 66:2363–2367

    Article  CAS  Google Scholar 

  • Umemura K, Usami H, Tomoda Y, Tanino S (2012) Compositions inducing plant disease & minus; resistance and process for producing the same. EP Patent, EP1421850B1

    Google Scholar 

  • Vega FE, Posada F, Peterson SW, Gianfagna TJ, Chaves F (2006) Penicillium species endophytic in coffee plants and ochratoxin A production. Mycologia 98(1):31–42

    Article  CAS  Google Scholar 

  • Voříšková A, Jansa J, Püschel D, Krüger M, Cajthaml T, Vosátka M, Janoušková M (2017) Real-time PCR quantification of arbuscular mycorrhizal fungi: does the use of nuclear or mitochondrial markers make a difference? Mycorrhiza 27(6):577–585

    Article  Google Scholar 

  • Vujanovic V, Germida JJ (2014) Endophytic microbial symbionts in plant prenatal care. WO Patent, WO2014121366A1

    Google Scholar 

  • Waqas M, Khan AL, Hamayun M, Shahzad R, Kang S-M, Kim J-G, Lee I-J (2015) Endophytic fungi promote plant growth and mitigate the adverse effects of stem rot: an example of Penicillium citrinum and Aspergillus terreus. J Plant Interact 10(1):280–287

    Article  CAS  Google Scholar 

  • West CP, Piper EL (2008) Non-toxic endophytes, plants injected therewith and methods for injecting plants. US Patent, US7465855B2

    Google Scholar 

  • West CP, Piper EL (2009) Non-toxic endophytes, plants injected therewith and methods for injecting plants. US Patent, US7553654B2

    Google Scholar 

  • West CP, Piper EL (2011) Non-toxic endophytes, plants injected therewith and methods for injecting plants. Us Patent, US7977550B2

    Google Scholar 

  • Wilson D (1995) Endophyte – the evolution of a term, and clarification of its use and definition. Oikos 73:274–276

    Article  Google Scholar 

  • Xianrong W (2016) A compound in the manufacture of a medicament for the treatment of ovarian cancer. CN Patent, CN103520178B

    Google Scholar 

  • Yadav V, Kumar M, Deep DK, Kumar H, Sharma R, Tripathi T, Tuteja N, Saxena AK, Johri AK (2010) A phosphate transporter from the root endophytic fungus Piriformospora indica plays a role in phosphate transport to the host plant. J Biol Chem 285:26532–26544

    Article  CAS  Google Scholar 

  • Yan Z (2014) Application of compound in preparation of drug for treating liver cancer. CN Patent, CN103536598A

    Google Scholar 

  • Young C, Hopkins A (2008a) Fungal endophytes of elymus Canadensis. WO Patent, WO2008100892A2

    Google Scholar 

  • Young C, Hopkins A (2008b) Fungal endophytes of elymus Canadensis. WO Patent, WO2008100892A3

    Google Scholar 

  • Young C, Hopkins A (2011) Fungal endophytes of Elymus canadensis. US Patent, US7892813B2

    Google Scholar 

  • Zhao W, Xiaomin W, Guanying S, Huan ZS, Hui Y, Hongyuan Z, Yue Z, Jing L (2017) One kind of endophyte ts4 and secondary metabolites, the preparation method and application toon. CN Patent, CN106754413A

    Google Scholar 

  • Zhi L, Xiping W (2017) Application endophyte and its control botrytis in grapes grape. CN Patent, CN106893678A

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Laith Khalil Tawfeeq Al-Ani .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Al-Ani, L.K.T. (2019). Recent Patents on Endophytic Fungi and Their International Market. In: Singh, H., Keswani, C., Singh, S. (eds) Intellectual Property Issues in Microbiology. Springer, Singapore. https://doi.org/10.1007/978-981-13-7466-1_14

Download citation

Publish with us

Policies and ethics