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Diagnosis of Liver Disease pp 269–275Cite as

Metastatic Liver Tumors

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Abstract

Metastatic tumors are the most common type of malignancy in the liver, far exceeding primary tumors of the liver. The distinction between a primary tumor and a metastatic tumor in the liver has both therapeutic and prognostic significance. Knowledge of the primary tumor site and its morphology, if available, is important in evaluating and comparing it to its metastasis. Among tumor types, adenocarcinoma, neuroendocrine tumor, and lymphoma are the most common. Common primary sites include the colon (adenocarcinoma), pancreas (adenocarcinoma and pancreatic neuroendocrine tumor), stomach and small intestine (adenocarcinoma, neuroendocrine and gastrointestinal stromal tumor), lung (adenocarcinoma, small-cell and large-cell neuroendocrine carcinoma, and squamous cell carcinoma), breast, skin (melanoma), and kidney (renal cell carcinoma).

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Abbreviations

AFP:

Alpha-fetoprotein

ALT:

Alanine aminotransferase

AST:

Aspartate aminotransferase

CK:

Cytokeratin

CT:

Computed tomography

GGT:

Gamma-glutamyl transferase

LDH:

Lactate dehydrogenase

TBIL:

Total bilirubin

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Acknowledgement

Prof. Alex Y. Chang was a coauthor of the first edition of this chapter.

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Authors and Affiliations

  1. New Hampshire, USA

    Louis J. Vaickus MD, PhD & Arief A. Suriawinata MD

  2. Gastroenterology, Hepatology and Internal Medicine, Iwai Clinic, Kyoto, Japan

    Masaki Iwai MD, PhD

Authors
  1. Louis J. Vaickus MD, PhD
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  2. Arief A. Suriawinata MD
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  3. Masaki Iwai MD, PhD
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Corresponding author

Correspondence to Arief A. Suriawinata MD .

Editor information

Editors and Affiliations

  1. Department of Gastroenterology & Hepatology, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan

    Etsuko Hashimoto

  2. Department of Gastroenterology/Hepatology, Stanford University School of Medicine, Palo Alto, CA, USA

    Paul Y. Kwo

  3. Department of Pathology and Laboratory Medicine, Dartmouth–Hitchcock Medical Center, Lebanon, NH, USA

    Arief A. Suriawinata

  4. Department of Pathology, Caritas Medical Center, Kowloon, Hong Kong, China

    Wilson M.S. Tsui

  5. Division of Gastroenterology, Hepatology & Internal Medicine, Iwai Clinic, Kamigyo-ku, Kyoto, Japan

    Masaki Iwai

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© 2019 Springer Nature Singapore Pte Ltd.

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Vaickus, L.J., Suriawinata, A.A., Iwai, M. (2019). Metastatic Liver Tumors. In: Hashimoto, E., Kwo, P., Suriawinata, A., Tsui, W., Iwai, M. (eds) Diagnosis of Liver Disease. Springer, Singapore. https://doi.org/10.1007/978-981-13-6806-6_18

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  • DOI: https://doi.org/10.1007/978-981-13-6806-6_18

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-13-6805-9

  • Online ISBN: 978-981-13-6806-6

  • eBook Packages: MedicineMedicine (R0)

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