Abstract
The liver weighing 1200–1500 g is the largest organ in the human adult and occupies about 2% of body weight. There are two anatomical lobes in the liver, right and left, with the right lobe six times in volume than the left lobe. The right and left lobes are separated anteriorly by the falciform ligament, posteriorly by ligamentum venosum, and inferiorly by ligamentum teres. The Couinaud classification [1] defines eight segments of the liver, and the Bismuth classification [2] divides it into four sectors; they are subdivided into right anterior (V and VIII), right posterior (VI and VII), left medial (IV), or left lateral (II and III) segment and caudate lobe (I) (Fig. 1.1).
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Abbreviations
- AFP:
-
Alpha fetoprotein
- cAMP:
-
cyclic adenosine 3′,5′-monophosphate
- cGMP:
-
cyclic guanosine 3′,5′-monophosphate
- Cx:
-
Connexin
- EGFR:
-
Epidermal growth factor receptor
- GVHD:
-
Graft-versus-host disease
- HCV:
-
Hepatitis C virus
- IL-6:
-
Interleukin-6
- JAMs:
-
Junctional adhesion molecules
- PDZ:
-
Postsynaptic density 95; Discs large, zonula occludens
- PKC:
-
Protein kinase C
- PSC:
-
Primary sclerosing cholangitis
- SR-BI:
-
Scavenger receptor BI
- TNF:
-
Tumor necrosis factor
- ZO:
-
Zonula occludens
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Iwai, M., Kojima, T., Suriawinata, A.A. (2019). Anatomy and Function. In: Hashimoto, E., Kwo, P., Suriawinata, A., Tsui, W., Iwai, M. (eds) Diagnosis of Liver Disease. Springer, Singapore. https://doi.org/10.1007/978-981-13-6806-6_1
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