Abstract
Hyaluronic acid (HA) filler is a soft-tissue filler that is used in >80% of the market. Since the US Food and Drug Administration approved Restylane (Q Med Company, Sweden) in 2003, HA fillers made of cross-linked HA have been commonly used because of their superior safety compared to other PMMA, PAAG, PCL, and PLLA fillers. Another advantage of HA fillers is that they can be dissolved in case of unexpected results, such as undesired outcomes or complications.
Clinicians should be educated about the fundamental manufacturing process and basic properties of hyaluronic acid fillers to prepare them for cases of complications. In this chapter, we will discuss the basic properties and associated complications of HA fillers and describe hyaluronidase, the most important drug used to treat such complications.
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Koh, I.S., Lee, W. (2019). Hyaluronic Acid Filler and Hyaluronidase. In: Filler Complications. Springer, Singapore. https://doi.org/10.1007/978-981-13-6639-0_2
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DOI: https://doi.org/10.1007/978-981-13-6639-0_2
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