Multiprotein Complexes

  • Natalya Kurochkina


Cell processes involve assembly of many components and coordination of their function. Protein complexes assemble and disassemble in response to various signals. Complexes are necessary to sort and target cargoes to cellular organelles, move molecules along filaments, exchange and recycle materials between cellular compartments, handle degradation of toxic molecules, provide signaling and communication inside the cell and between cells. They consist of tens or even hundreds of proteins and their ligands which work in accord to support life functions. Formation of multiprotein complexes is regulated by posttranslational modifications and depends on protein interactions. This chapter describes molecular assemblies involved in vital cellular processes.


Complex Assembly Cellular organelle Filament Protein interactions 


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© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Natalya Kurochkina
    • 1
  1. 1.Department of BiophysicsSchool of Theoretical ModelingWashington, DCUSA

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