Abstract
Mushrooms have been used globally for various nutritional and medicinal values and now are gaining worldwide recognition due to its various health benefits and potent and unique pharmaceutical properties. Researchers in different parts of the world have demonstrated different species of mushrooms possessing immunomodulatory, antitumor, anticancer, antibacterial, antiviral, anti-inflammatory, anti-atherosclerotic, neuroprotective, antioxidant, and anti-hypoglycemic properties. The chapter presents an overview of the research on the therapeutic efficacy of mushrooms.
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Abbreviations
- AD:
-
Alzheimer’s disease
- APP:
-
Amyloid precursor protein
- BACE1:
-
Beta-secretase 1
- BDNF:
-
Brain-derived neurotrophic factor
- CA3:
-
Cornu amonis
- CAT:
-
Catalase
- CCL4:
-
Carbon tetrachloride
- CNS:
-
Central nervous system
- COMT:
-
Catechol-O-methyltransferase
- EMM:
-
Ectomycorrhizal mushrooms
- GDNF:
-
Glia-derived neurotrophic factor
- GIT:
-
Gastrointestinal tract
- GSH:
-
Glutathione
- HCC:
-
Hepatocellular carcinoma
- HDL:
-
High-density lipoprotein
- HFD:
-
High-fat diet
- HIV:
-
Human immunodeficiency virus
- HMG-CoA:
-
Hydroxymethylglutaryl-CoA
- IFN-γ:
-
Interferon-gamma
- iNOS:
-
Inducible nitric oxide synthase
- JNK:
-
c-Jun N-terminal kinases
- LDL:
-
Low-density lipoprotein
- LPS:
-
Lipopolysaccharide
- MAPK:
-
Mitogen-activated protein kinase
- MPTP:
-
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- MRSA:
-
Methicillin-resistant Staphylococcus aureus
- NDC:
-
Non-digestible carbohydrates
- NF-κB:
-
Nuclear factor-κB
- NGF:
-
Nerve growth factor
- NK:
-
Natural killer cells
- NO:
-
Nitric oxide
- NPC:
-
Neural progenitor cells
- PI3K:
-
Phosphatidylinositol-4,5-bisphosphate 3-kinase
- PKC:
-
Protein kinase C
- RFA:
-
Radio frequency ablation
- RNA:
-
Ribonucleic acid
- ROS:
-
Reactive oxygen species
- SOD:
-
Superoxide dismutase
- TC:
-
Total cholesterol
- TD1:
-
Type 1 diabetes mellitus
- TD2:
-
Type 2 diabetes mellitus
- Th1/Th2:
-
T-helper cells
- TNF-α:
-
Tumor necrosis factor-alpha
- UDP:
-
Uridine diphosphate
- VEGF:
-
Vascular endothelial growth factor
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Ramesh, S. et al. (2019). Overview of Therapeutic Efficacy of Mushrooms. In: Agrawal, D., Dhanasekaran, M. (eds) Medicinal Mushrooms. Springer, Singapore. https://doi.org/10.1007/978-981-13-6382-5_3
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