Abstract
Soon after closure, the cephalic end of the neural tube expands to form three primary vesicles, prosencephalon, mesencephalon and rhombencephalon. They are the progenitors of the forebrain, midbrain and hindbrain, respectively. The prosencephalon, during 4–10 weeks of gestation, develops by the process of ventral induction which includes formation, cleavage and midline development. Failure of formation results in aprosencephaly or atelencephaly. Total or partial failure of cleavage results in the spectrum of holoprosencephaly. Abnormal midline development results in agenesis of CC or septal agenesis. Holoprosencephaly is dealt with in Chap. 3. Anomalies of the CC and septum pellucidum will be described in this chapter.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Karl K, Esser T, Heling KS, Chaoui R. Cavum septi pellucidi (CSP) ratio: a marker for partial agenesis of the fetal corpus callosum. Ultrasound Obstet Gynecol. 2007;50:336–41.
Pilu G, Tani G, Carletti A, Malaigia S, Ghi T, Rizzo N. Difficult early sonographic diagnosis of absence of the fetal septum pellucidum. Ultrasound Obstet Gynecol. 2005;25:70–2.
Malinger G, Lev D, Kidron D, Heredia F, Hershkovitz R, Lerman-Sagie T. Differential diagnosis in fetuses with absent septum pellucidum. Ultrasound Obstet Gynecol. 2005;25:42–9.
Malinger G, Lev D, Oren M, Lerman-Sagie T. Non-visualization of the cavum septi pellucidi is not synonymous with agenesis of the corpus callosum. Ultrasound Obstet Gynecol. 2012;40:165–70.
Paladini D, Pastore G, Cavallaro A, Massaro M, Nappi C. Agenesis of the fetal corpus callosum: sonographic signs change with advancing gestational age. Ultrasound Obstet Gynecol. 2013;42:687–90.
Lepinard C, Coutant R, Boussion F, Loisel D, Delorme B, Biquard F, Bonneau D, Guichet A, Descamps P. Prenatal diagnosis of absence of the septum pellucidum associated with septo-optic dysplasia. Ultrasound Obstet Gynecol. 2005;25:73–5.
Lerman-Sagie T, Ben-Sira L, Achiron R, Schreiber L, Hermann G, Lev D, Kidron D, Malinger G. Thick fetal corpus callosum: an ominous sign? Ultrasound Obstet Gynecol. 2009;34:55–61.
Pilu G, Sandri F, Perolo A, Pittalis MC, Grisolia G, Cocchi G, Foschini MP, Salvioli GP, Bovicelli L. Sonography of fetal agenesis of the corpus callosum: a survey of 35 cases. Ultrasound Obstet Gynecol. 1993;1:318–29.
Shen O, Gelot AB, Moutard ML, Jouannic JM, Sela HY, Garel C. Abnormal shape of the cavum septi pellucidi: an indirect sign of partial agenesis of the corpus callosum. Ultrasound Obstet Gynecol. 2015;46:595–9.
Ghi T, Carletti A, Contro E, Cera E, Falco P, Tagliavini G, Michelacci L, Tani G, Youssef A, Bonasoni P, Rizzo N, Pelusi G, Pilu G. Prenatal diagnosis and outcome of partial agenesis and hypoplasia of the corpus callosum. Ultrasound Obstet Gynecol. 2010;35:35–41.
Malinger G, Zakut H. The corpus callosum: normal fetal development as shown by transvaginal sonography. AJR. 1993;161:1041–3.
Cignini P, Padula F, Giorlandino M, Brutti P, Alfo M, Giannarelli D, Mastrandrea ML, D’Emidio L, Vacca L, Aloisis A, Giorlandino C. Reference charts for fetal corpus callosum length. J Ultrasound Med. 2014;33:1065–78.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Rama Murthy, B.S. (2019). Anomalies of Corpus Callosum and Septum Pellucidum. In: Imaging of Fetal Brain and Spine. Springer, Singapore. https://doi.org/10.1007/978-981-13-5844-9_2
Download citation
DOI: https://doi.org/10.1007/978-981-13-5844-9_2
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-13-5843-2
Online ISBN: 978-981-13-5844-9
eBook Packages: MedicineMedicine (R0)