Skip to main content

Biosensors and its Transducers

  • Chapter

Abstract

The practice of medicine has changed dramatically over the past decades with the drastic development in the field of biosensors. It had a significant impact on all aspects of the healthcare sector. The concern about the detection of chemical or biological important compounds and their need is expanded from clinical diagnostics to personal care/point care devices. Assessment of health and functioning is one of the growing apprehensions in the common population. With the expanding of technology every day, it is possible to take healthcare technology to the doorstep of the patient. Consider a few examples that are important in today’s lifestyle: a diabetic monitor/glucometer, pregnancy strips, insulin drug administrator, biochips, etc. Other significant developments include the use of protein/other biomolecules as a device component (biorecognition element) rather than constituents of a living cell and the application of production methods such as screen printing that can manufacture a very large number of sensors with a high degree of reproducibility. These studies had further become a prerequisite for design and development in biosensors field to emerge as a commercial product from the laboratory. The application of biosensors now has also broadened with time from clinical diagnostics to environmental monitoring, food industry, agriculture, textile industry, water management and many more.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   139.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   179.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Baldrich E (2010) Aptamers: versatile tools for reagentlessaptasensing. In: Recognition receptors in biosensors. Springer, New York, pp 675–722

    Chapter  Google Scholar 

  • Brett C, Oliveira Brett AM (1993) Electrochemistry: principles, methods, and applications (No. 544.6 BRE).

    Google Scholar 

  • Cliquet P (2004) Development of immune detection assays for penicillins and sulfonamides in food of animal origin Doctor in Veter inary Sciences, UGent 2004. Promotors Cox E and Goddeeris B.

    Google Scholar 

  • Drummond TG, Hill MG, Barton JK (2003) Electrochemical DNA sensors. Nat Biotechnol 21(10):1192

    Article  CAS  Google Scholar 

  • Eggins BR (2008) Chemical sensors and biosensors, vol 28. Wiley, Chichester

    Google Scholar 

  • Feng L, Wu L, Wang J, Ren J, Miyoshi D, Sugimoto N, Qu X (2012) Detection of a prognostic indicator in early stage cancer using functionalized graphene based peptide sensors. Adv Mat 24(1):125–131

    Article  CAS  Google Scholar 

  • Gorton L (ed) (2005) Biosensors and modern biospecific analytical techniques, vol 44. Elsevier, Amsterdam

    Google Scholar 

  • Hong J, Yoon DS, Park MI, Choi J, Kim TS, Im G, Kim S, Pak YE, No K (2004) A dielectric biosensor using the capacitance change with AC frequency integrated on glass substrates. Jpn J Appl Phy 43(8R):5639

    Article  CAS  Google Scholar 

  • http://wirelesslifesciences.org/2015/03/oj-bio-at-wlsa-convergence-summit-2015/

  • https://www.easybiologyclass.com/enzyme-cell-immobilization-techniques

  • Ju H, Zhang X, Wang J (2011) NanoBiosensing: principles, development and application. Springer, New York

    Book  Google Scholar 

  • Kaisti M (2017) Detection principles of biological and chemical FET sensors. Biosen Bioelectron 98:437–448

    Article  CAS  Google Scholar 

  • Kell D (1988) Biosensors. Fundamentals and applications. Turner APF, Karube I, Wilson GS (eds), Oxford University Press, Oxford.

    Google Scholar 

  • Kissinger PT, Heineman WR (1983) Cyclic voltammetry. J Chem Educ 60(9):702

    Article  CAS  Google Scholar 

  • Lai Y, Wang L, Liu Y, Yang G, Tang C, Deng Y, Li S (2018) Immuno sensors based on nanomaterials for detection of tumor markers. J Biomed Nanotechnol 14(1):44–65

    Article  CAS  Google Scholar 

  • Lee K, Povlich LK, Kim J (2007) Label-free and self-signal amplifying molecular DNA sensors based on bio conjugated polyelectrolyte. Adv Func Mat 17(14):2580–2258

    Article  CAS  Google Scholar 

  • Mao X, Ma Y, Zhang A, Zhang L, Zeng L, Liu G (2009) Disposable nucleic acid biosensors based on gold nanoparticle probes and lateral flow strip. Anal Chem 81(4):1660–1668

    Article  CAS  Google Scholar 

  • Martins TD, Ribeiro ACC, de Camargo HS, da Costa Filho PA, Cavalcante HPM, Dias DL (2013) New insights on optical biosensors: techniques, construction and application. In: State of the art in biosensors-general aspects. In Tech, Croatia

    Google Scholar 

  • Nguyen H, Park J, Kang S, Kim M (2015) Surface plasmon resonance: a versatile technique for biosensor applications. Sensors 15(5):10481–10510

    Article  CAS  Google Scholar 

  • Pancrazio JJ, Whelan JP, Borkholder DA, Ma W, Stenger DA (1999) Development and application of cell-based biosensors. Ann Biomed Eng 27(6):697–711

    Article  CAS  Google Scholar 

  • Patel S, Nanda R, Sahoo S, Mohapatra E (2016) Biosensors in health care: the milestones achieved in their development towards lab-on-chip-analysis. Biochem Res Int 2016

    Google Scholar 

  • Schöning MJ, Poghossian A (2002) Recent advances in biologically sensitive field-effect transistors (BioFETs). Analyst 127(9):1137–1151

    Article  Google Scholar 

  • Sun D, Lu J, Zhong Y, Yu Y, Wang Y, Zhang B, Chen Z (2016) Sensitive electrochemical aptamer cytosensor for highly specific detection of cancer cells based on the hybrid nanoelectrocatalysts and enzyme for signal amplification. Biosen Bioelectron 75:301–307

    Article  CAS  Google Scholar 

  • Thévenot DR, Toth K, Durst RA, Wilson GS (2001) Electrochemical biosensors: recommended definitions and classification. Anal Lett 34(5):635–659

    Article  Google Scholar 

  • Wang J (2008) Electrochemical glucose biosensors. Chem Rev 108(2):814–825

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gopu Govindasamy .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Singapore Pte Ltd.

About this chapter

Cite this chapter

Janani Viswananthan, Govindasamy, G. (2019). Biosensors and its Transducers. In: Paul, S. (eds) Biomedical Engineering and its Applications in Healthcare. Springer, Singapore. https://doi.org/10.1007/978-981-13-3705-5_6

Download citation

Publish with us

Policies and ethics