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Pregnancy and Neuroanesthesia

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Abstract

Perioperative management of pregnant patients, who require a neurosurgical intervention, poses several unique challenges for the neuroanesthetist. Besides the standard neuroanesthesia concerns, the delicate feto-maternal homeostasis has to be maintained, in order to achieve a good maternal outcome without compromising fetal safety. This may necessitate several modifications in the conventional neuroanesthesia technique and, often, a need to skillfully balance, competing or even contradictory clinical goals. Other pertinent dilemma that arises during management includes decisions regarding the optimal timing of neurosurgery, continuation or termination of pregnancy, optimal timing and mode of delivery, and possibility of a combined cesarean section and neurosurgery in patients with near-term pregnancy. Moreover, there are no well-established recommendations that can help to guide the management of these patients. Optimal perioperative management in these circumstances mandates an integrated understanding not only of neurosurgical anesthesia but also of the maternal physiological changes during pregnancy and their implications on feto-maternal homeostasis, intracranial pathology, and the neuroanesthesia technique, along with the pertinent perioperative fetal concerns and the effect of anesthetic drugs on feto-maternal physiology and cerebral homeostasis; importantly, a well-planned, individualized, and multidisciplinary approach is vital for a favorable outcome. The initial sections of this chapter provide an overview of the basic fundamentals; the latter sections describe the principles of anesthetic management for pregnant patients during a cranial surgery, a combined cesarean section and neurosurgery, spinal surgery, neuroendovascular procedure, and traumatic brain/spinal cord injury.

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References

  1. Gaiser R. Physiologic changes of pregnancy. In: Chestnut DH, Won CA, Beiling Y, Tsen LC, et al., editors. Chestnut’s obstetric anesthesia: principles and practice. 5th ed. Philadelphia: Elsevier Saunders; 2014. p. 25–38.

    Google Scholar 

  2. Brooks VL, Dampney RA, Heesch CM. Pregnancy and the endocrine regulation of the baroreceptor reflex. Am J Physiol Regul Integr Comp Physiol. 2010;299:R439–51.

    Article  CAS  Google Scholar 

  3. Priya SP, Nelson PC, Heli T, et al. Physiological changes in pregnancy. Cardiovasc J Afr. 2016;27(2):89–94.

    Article  Google Scholar 

  4. Cluver C, Novikova N, Hofmeyr GJ, Hall DR. Maternal position during caesarean section for preventing maternal and neonatal complications. Cochrane Database Syst Rev. 2013;(3):CD007623. https://doi.org/10.1002/14651858.CD007623.pub3.

  5. Mushambi MC, Kinsella SM, Popat M, et al. Obstetric Anaesthetists’ Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics. Anaesthesia. 2015;70(1):1286–306.

    Article  CAS  Google Scholar 

  6. Templeton A, Kelman GR. Maternal blood-gases, (PaO2–PaO2), physiological shunt and VD/VT in normal pregnancy. Br J Anaesth. 1976;48:1001–4.

    Article  CAS  Google Scholar 

  7. Archer GW, Marx GF. Arterial oxygen tension during apnoea in parturient women. Br J Anaesth. 1974;46:358–60.

    Article  Google Scholar 

  8. Reitman E, Flood P. Anaesthetic considerations for non-obstetric surgery during pregnancy. Br J Anaesth. 2011;107(Suppl 1):i72–8.

    Article  Google Scholar 

  9. Nejdlova M, Johnson T. Anaesthesia for non-obstetric procedures during pregnancy. Contin Educ Anaesth Crit Care Pain. 2012;12(4):203–6.

    Article  Google Scholar 

  10. Upadaya M, Saneesh PJ. Anaesthesia for non-obstetric surgery during pregnancy. Indian J Anaesth. 2016;60(4):234–41.

    Article  Google Scholar 

  11. American College of Obstetricians and Gynecologists. Nonobstetric surgery during pregnancy. Committee opinion no. 696. Obstet Gynecol. 2017;129:777–8.

    Article  Google Scholar 

  12. Wang LP, Paech MJ. Neuroanesthesia for pregnant women. Anesth Analg. 2008;107:193–200.

    Article  Google Scholar 

  13. Tawfik MM, Badran BA, Eisa AA, Barakat RI. Simultaneous cesarean delivery and craniotomy in a term pregnant patient with traumatic brain injury. Saudi J Anaesth. 2015;9:207–10.

    Article  Google Scholar 

  14. Jentink J, Loane MA, Dolk H, Barisic I, Garne E, Morris JK, de Jong-van den Berg LT, EUROCAT Antiepileptic Study Working Group, et al. Valproic acid monotherapy in pregnancy and major congenital malformations. N Engl J Med. 2010;362:2185–9.

    Article  CAS  Google Scholar 

  15. Cooper WO, Hernandez-Diaz S, Arbogast PG, Dudley JA, Dyer S, Gideon PS, et al. Major congenital malformations after first-trimester exposure to ACE inhibitors. N Engl J Med. 2006;354:2443–51.

    Article  CAS  Google Scholar 

  16. American College of Obstetricians and Gynecologists. Guidelines for diagnostic imaging during pregnancy and lactation. Committee opinion no. 723. Obstet Gynecol. 2017;130:e210–6.

    Article  Google Scholar 

  17. Fukuda K, Masuoka J, Takada S, Katsuragi S, Ikeda T, Iihara K, et al. Utility of intraoperative fetal heart rate monitoring for cerebral arteriovenous malformation surgery during pregnancy. Neurol Med Chir (Tokyo). 2014;54:819–23.

    Article  Google Scholar 

  18. Ayres-de-Campos D, Spong CY, Chandraharan E. FIGO consensus guidelines on intrapartum fetal monitoring: Cardiotocography. Int J Gynecol Obstet. 2015;131(1):13–24.

    Article  Google Scholar 

  19. Nossek E, Ekstein M, Rimon E, Kupferminc MJ, Ram Z. Neurosurgery and pregnancy. Acta Neurochir. 2011;153:1727–35.

    Article  Google Scholar 

  20. Qaiser R, Black P. Neurosurgery in pregnancy. Semin Neurol. 2007;27:476–81.

    Article  Google Scholar 

  21. Bateman BT, Olbrecht VA, Berman MF, et al. Peripartum subarachnoid hemorrhage: nationwide data and institutional experience. Anesthesiology. 2012;116:324–33.

    Article  Google Scholar 

  22. Pereira CE, Lynch JC. Management strategies for neoplastic and vascular brain lesions presenting during pregnancy: a series of 29 patients. Surg Neurol Int. 2017;8:27.

    Article  Google Scholar 

  23. Barbarite E, Hussain S, Dellarole A, Elhammady MS, Peterson E. The management of intracranial aneurysms during pregnancy: a systematic review. Turk Neurosurg. 2016;26(04):465–74.

    PubMed  Google Scholar 

  24. Robba C, Bacigaluppi S, Bragazzi NL, Bilotta F, Sekhon MS, Bertuetti R, et al. Aneurysmal subarachnoid haemorrhage in pregnancy – case series, review and pooled data analysis. World Neurosurg. 2016;88:383–98.

    Article  Google Scholar 

  25. Khoi D, Than KD, Thompson BG Jr. Pregnancy and the vascular lesion. In: Win HR, editor. Youmans neurological surgery, vol. 4. 6th ed. Philadelphia: Elsevier Saunders; 2011. p. 4203–6.

    Google Scholar 

  26. Olivi A, Bydon M, Raza SM. Brain tumors during pregnancy. In: Win HR, editor. Youmans neurological surgery, vol. 2. 6th ed. Philadelphia: Elsevier Saunders; 2011. p. 1229–35.

    Chapter  Google Scholar 

  27. Abd-Elsayed AA, Díaz-Gómez J, Barnett GH, et al. A case series discussing the anaesthetic management of pregnant patients with brain tumours. F1000Research. 2013;2:92.

    Article  Google Scholar 

  28. Kazemi P, Villar G, Flexman AM. Anesthetic management of neurosurgical procedures during pregnancy: a case series. J Neurosurg Anesthesiol. 2014;26:234–40.

    Article  Google Scholar 

  29. Ng J, Kitchen N. Neurosurgery and pregnancy. J Neurol Neurosurg Psychiatry. 2008;79:745–52.

    Article  CAS  Google Scholar 

  30. Rosen MA. Management of anesthesia for the pregnant surgical patient. Anesthesiology. 1999;91:1159–63.

    Article  CAS  Google Scholar 

  31. Han IH, Kuh SU, Kim JH, et al. Clinical approach and surgical strategy for spinal diseases in pregnant women: a report of ten cases. Spine (Phila Pa 1976). 2008;33(17):E614–9.

    Article  Google Scholar 

  32. Speirs E, Wiles M, Bacon A, Radley S. Positioning a proned patient with cauda equina syndrome who presents at 15 weeks gestation: a case report [v1; ref status: indexed, http://f1000r.es/2qn]. F1000Research. 2014;3:117.

    Article  Google Scholar 

  33. Wang P, Xin XT, Lan H, et al. Spontaneous cervical epidural hematoma during pregnancy: case report and literature review. Eur Spine J. 2011;20:S176–9.

    Article  Google Scholar 

  34. Ikossi DG, Lazar AA, Morabito D, Fildes J, Knudson MM. Profiles of mothers at risk: an analysis of injury and pregnancy loss in 1,195 trauma patients. J Am Coll Surg. 2005;200:49–56.

    Article  Google Scholar 

  35. Wisoff JH, Kratzert KJ, Handwerker SM, Young BK, Epstein F. Pregnancy in patients with cerebrospinal fluid shunts: report of a series and review of the literature. Neurosurgery. 1991;29:827–31.

    Article  CAS  Google Scholar 

  36. Krauss P, Fritz-Naville M, Regli L, Stieglitz LH. Progressive functional underdrainage in cerebrospinal fluid shunt-dependent women during pregnancy: case report and review of the literature. World Neurosurg. 2018;109:372–6.

    Article  Google Scholar 

  37. Van de Velde M, de Buck F. Anesthesia for non-obstetric surgery in the pregnant patient. Minerva Anestesiol. 2007;73:235–40.

    Google Scholar 

  38. Zaouter C, Calderon J, Hemmerling TM. Videolaryngoscopy as a new standard of care. Br J Anaesth. 2015;114:181–3.

    Article  CAS  Google Scholar 

  39. Jeejeebhoy FM, Zelop CM, Lipman S, Carvalho B, Joglar J, Mhyre JM, et al. Cardiac arrest in pregnancy: a scientific statement from the American Heart Association. Circulation. 2015;132:1747–73. https://doi.org/10.1161/CIR.0000000000000300.

    Article  PubMed  Google Scholar 

  40. Boker A, Ong BY. Anaesthesia for Cesarean section and posterior fossa craniotomy in a patient with von Hippel-Lindau disease. Can J Anaesth. 2001;48:387–90.

    Article  CAS  Google Scholar 

  41. Van de Velde M, Teunkens A, Kuypers M, Dewinter T, Vandermersch E. General anaesthesia with target controlled infusion of propofol for planned caesarean section: maternal and neonatal effects of a remifentanil-based technique. Int J Obstet Anesth. 2004;13:153–8.

    Article  Google Scholar 

  42. Laurence AG, Marshman A, Aspoas R, Manjir SR, Chawda SJ. The implications of ISAT and ISUIA for the management of cerebral aneurysms during pregnancy. Neurosurg Rev. 2007;30:177–80.

    Article  Google Scholar 

  43. Vougioukas VI, Kyroussis G, Glasker S, et al. Neurosurgical interventions during pregnancy and the puerperium: clinical considerations and management. Acta Neurochir. 2004;146:1287–91.

    Article  CAS  Google Scholar 

  44. Kanas M, Kunzle H, Martins DE. Diskectomy during pregnancy: case report and review of the literature. Global Spine J. 2015;5(2):130–4.

    Article  Google Scholar 

  45. Barraco RD, Chiu WC, Clancy TV, Como JJ, Ebert JB, Hess LW, et al. Practice management guidelines for the diagnosis and management of injury in the pregnant patient: the EAST practice management guidelines work group. J Trauma. 2010;69:211–4.

    Article  Google Scholar 

  46. Himmelseher S, Kuczkowski KM. Trauma in pregnancy. In: Kuczkowski KM, Drobnik L, editors. International textbook of obstetric anesthesia and perinatal medicine. Warsaw: Medmedia; 2010. p. 17–27.

    Google Scholar 

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Tandon, M.S., Dhingra, A. (2019). Pregnancy and Neuroanesthesia. In: Prabhakar, H., Ali, Z. (eds) Textbook of Neuroanesthesia and Neurocritical Care. Springer, Singapore. https://doi.org/10.1007/978-981-13-3387-3_19

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  • DOI: https://doi.org/10.1007/978-981-13-3387-3_19

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  • Online ISBN: 978-981-13-3387-3

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