Abstract
FONs have been highly attractive for cell imaging, chemosensing and drug delivery applications among others. Several polyethylene glycolated (PEGylated) AIE-based, biocompatible polydopamine, cross-linkable chitosan-based AIE dye, AIE dye-based, self-assembled π-conjugated and self-assembled amphiphilic fluorene oligomeric FONs have been studied for cell imaging applications. FONs have also been extensively studied as sensors, drug delivery systems and for other applications like photodynamic therapy and apoptosis inducers of cancer cells. In this chapter, attempts have been made to highlight the advances in the research on the development of FONs as preferred materials of choice for cell imaging, chemosensing (for inorganic cations and anions, and organic molecules and biological pathogens). Besides, efforts have been made to throw light on the applications of FONs as DDSs for different kinds of drugs including anticancer ones. The final section of this chapter is focused on the uses of FONs in photodynamic therapy, apoptosis induction and the study of blood–brain barrier damage.
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Wani, W.A., Shahid, M., Hussain, A., AlAjmi, M.F. (2018). Applications of Fluorescent Organic Nanoparticles. In: Fluorescent Organic Nanoparticles. SpringerBriefs in Materials. Springer, Singapore. https://doi.org/10.1007/978-981-13-2655-4_3
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