Abstract
Spinal cord stimulation (SCS) is a neuromodulation technique well established for the treatment of chronic pain syndromes and has been shown to be useful to treat movement disorders. Although the epidural electrodes do not invade the central nervous system, the implantation surgery has inherent risks requiring well trained staff and precise procedures to avoid spinal cord lesions. The major problem faced in experimental SCS device implantation in rats is the difficult access to the epidural area, making essential the development of a device that promotes a best column positioning and facilitates the fixation of the animal for spinal access. Here, we developed the SciTable, a spinal cord implantation table printed using Polylactic Acid (PLA). The surgery performance of three well trained surgeons during electrode implantation in rats showed significant improvement on animal stability, epidural area access and surgery time when the SciTable was used. Altogether, the results indicate that the use of the SciTable optimized the entire surgical procedure, which may positively impact animal survival and facilitate training of inexperienced surgeons. The continuous optimization of animal surgery is essential to safeguard animal welfare and to promote a faster development of the neuromodulation and neurosurgery fields.
Kim Mansur Yano and Severino Peixoto Nunes Netto are contributed equally to this work.
Fabrício Lima Brasil and Manuela Sales Lima Nascimento are Co-senior authors.
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Acknowledgements
This work was supported by the Santos Dumont Institute (M.S.L.N., M.F.P.A., and F.L.B.), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (F.C.M.) and Brazil Ministry of Education (MEC). The group also thank the Julio Melo from the Prototyping Laboratory (Protolab), Federal University of Rio Grande do Norte.
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Yano, K.M. et al. (2019). SciTable: A 3D Printed Surgical Table for Spinal Cord Implant Procedures. In: Costa-Felix, R., Machado, J., Alvarenga, A. (eds) XXVI Brazilian Congress on Biomedical Engineering. IFMBE Proceedings, vol 70/2. Springer, Singapore. https://doi.org/10.1007/978-981-13-2517-5_94
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DOI: https://doi.org/10.1007/978-981-13-2517-5_94
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