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The Journey of Vaccines

  • Lingsheng CaoEmail author
  • Lei Cao
Chapter
  • 136 Downloads
Part of the Public Health in China book series (PUBHECH, volume 3)

Abstract

China, as country with the largest population in the world, is now becoming one of the largest producers and users of vaccines. Hundreds of millions of doses of vaccines are produced annually in China – not only to meet the needs in China but also to export to other countries [1, 2]. How are these “magic weapons” against infectious diseases produced? We know that vaccines are sensitive to heat and light, and therefore, how are these vaccines stored and transported? Here we introduce the journey of a vaccine, from production, storage, and transportation to finally being administered to an individual.

References

  1. 1.
    Wang Fu-qing, Yi Jing-wei, Zhao Xiao-yan, et al. The development status and perspective of vaccine industry in China. Chin J Biochem Pharm. 2009;30(4):287–90.Google Scholar
  2. 2.
    China Industry Research. Situation analysis and forecast prospect of vaccine industry development of China, 2016–2020. Beijing: China Industry Research; 2015.Google Scholar
  3. 3.
    Wei Xiao-lu. Production technology study on influenza vaccine (split virion) [D]. Beijing: Chinese Peking Union Medical College; 2008. p. 9–18.Google Scholar
  4. 4.
    Zhang Wen-jie. Study on applying homebred H7N9 avian vaccine strain in influenza vaccine manufacturing by mature process. Hangzhou: Zhejiang University of Technology; 2015. p. 9–58.Google Scholar
  5. 5.
    Wang Long-de, et al. Immunization practice and management. Beijing: People’s Medical Publishing House; 2006.Google Scholar
  6. 6.
    Cao Qing, Su Wan-nian. Strengthen the cold chain establishment and management, improve the quality of immunization program. Chin J Public Health. 1987;6(1):40–1.Google Scholar
  7. 7.
    Zhu Pei-lie. Overview of immunization (2). Cent Plains Med J. 1958;8:9–12.Google Scholar
  8. 8.
    PUJI Township Health Center, Lanzhou Biologicals. Observation of immunization effect of measles vaccine in winter under the condition of without cold chain. Biol Prod Inf. 1976;00:50–5.Google Scholar
  9. 9.
    Ministry of Health. Immunization practice regulations. 20 Sept 2005.Google Scholar
  10. 10.
    Beijing Municipal Commission of Health and Family Planning. An explanation of vaccine procurement and logistics management. 20 Mar 2016.Google Scholar
  11. 11.
    Shanghai Municipal Commission of Health and Family Planning. The notification to further improve the immunization and logistics management. 3 Nov 2016.Google Scholar
  12. 12.
    Tianjin Public Procurement Center. Competitive consultation announcement for category I and II vaccine distribution service project [EB/OL]. http://www.tjgpc.gov.cn/webInfo/getSearchWebInfoList1.do?keyWord=%E7%96%AB%E8%8B%97.
  13. 13.
    Ministry of Health. Vaccine storage and transportation management regulation [Z]. 8 Mar 2006.Google Scholar
  14. 14.
    Chinese Center for Disease Control and Prevention. With the help of the news media, propagandize scientific knowledge. (Report for supporting the Xinjiang Autonomous region). 1 July 2014. http://www.chinanip.org.cn/yjjs/201407/t20140701_98974.htm.
  15. 15.
    Ci Wei-lian. Establishment and improvement of EPI works in China. Chin J Prev Med. 2000;34(2):67–8.Google Scholar
  16. 16.
    Ministry of Foreign Trade and Economic Cooperation. EPI cooperation program in China goes well. Int Trade. 1995;10(1):40–5.Google Scholar
  17. 17.
    Xu Han-sun, Deng Zhu-qing, Liu Jun-hua, et al. The establishment and application of a real-time temperature monitoring system for regional vaccine cold chains. Mod Prev Med. 2014;41(14):2569–71.Google Scholar
  18. 18.
    Chen Wei, Gao Zhi-gang, Luo Xiao-yan, et al. Evaluation of the cold chain automatic monitor system in vaccination clinics. Chin J Vaccine Immunization. 2015;21(1):92–5.Google Scholar
  19. 19.
    Shu Jian-de. Vaccine Vial Monit. 2010;23(11):1275–6.Google Scholar
  20. 20.
    Sun Xiao-dong. The application of cold chain technique in vaccine management in Shanghai city [R]. Fuzhou: China Preventive Medicine Association; 2015.Google Scholar
  21. 21.
    Liang Xu. Issues research for pharmaceutical cold chain logistics in China. Price Issue. 2013;1:79–81.Google Scholar
  22. 22.
    State Council of the PRC. Regulations on the administration of vaccine and vaccination. 2016.Google Scholar
  23. 23.
    National Health and Family Planning Commission of the PRC. EPI operational standards. 2016, 5–11.Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. & People's Medical Publishing House, PR of China 2019

Authors and Affiliations

  1. 1.National Immunization Program, Chinese Center for Disease Control and PreventionBeijingChina

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