Trigeminal Neuralgia in Multiple Sclerosis

  • Nitasha Mishra


Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), affecting more than 2 million people worldwide [1]. It is punctuated by fully or partially reversible episodes of neurologic disability, usually lasting for days or weeks. The typical syndrome at presentation include, but is not limited to, monocular visual loss due to optic neuritis, limb weakness or sensory loss due to transverse myelitis, double vision due to brain-stem dysfunction, or ataxia due to a cerebellar lesion [2]. The association of TGN and multiple sclerosis (MS) has been well-known since the end of the nineteenth century [3]; a strong association has been suggested with a 20-fold higher prevalence of TGN in this group compared to the general population [4]. A systematic review [5] suggested a prevalence of 3.8% of TGN in patients with MS. Patients of TGN due to MS have been found to have a mean age 5.5 year less than those suffering from idiopathic TGN [6].


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Nitasha Mishra
    • 1
  1. 1.Department of AnaesthesiologyAll India Institute of Medical Sciences (AIIMS)BhubaneswarIndia

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