Complementary Medicine in Trigeminal Neuralgia

  • Rajeeb Kumar Mishra
  • Girija Prasad Rath


Trigeminal neuralgia (TGN) is a chronic debilitating condition characterized by recurrent attacks of lancinating pain in the distribution of the trigeminal nerve. Carbamazepine is the initial drug of choice for treating TGN [1]; however, several other drugs, including antidepressants may provide pain relief in some cases. Neurosurgical treatment may be helpful in treating drug-refractory cases. Apart from pharmacotherapy and surgical interventions, several complementary therapies provide additional benefit.


  1. 1.
    Wiffen PJ, McQuay HJ, Moore RA. Carbamazepine for acute and chronic pain. Cochrane Database Syst Rev. 2005:CD005451.Google Scholar
  2. 2.
    National center for complementary and integrative health. Complementary, alternative, or integrative health: what’s in a name? Available at: Accessed Jan 10, 2018.
  3. 3.
    Silenzio VMB. What is the role of complementary and alternative medicine in public health? Am J Public Health. 2002;92:1562–4.CrossRefGoogle Scholar
  4. 4.
    Ernst E, Lee MS, Choi TY. Acupuncture: does it alleviate pain and are there serious risks? A review of reviews. Pain. 2011;152:755–64.CrossRefGoogle Scholar
  5. 5.
    Cabýoglu MT, Ergene N, Tan U. The mechanism of acupuncture and clinical applications. Int J Neurosci. 2006;116:115–25.CrossRefGoogle Scholar
  6. 6.
    Tian LF. A survey on acupuncture treatment of trigeminal neuralgia. J Tradit Chin Med. 2010;30:68–76.CrossRefGoogle Scholar
  7. 7.
    Yang JX, Zhang JP, Yu JC, Han JX. Clinical research of primary trigeminal neuralgia treated with electroacupuncture at qi streets acupoints combined with spinal regulation therapy. Zhongguo Zhen Jiu. 2014;34:763–8.PubMedGoogle Scholar
  8. 8.
    Ahn CB, Lee SJ, Lee JC, Fossion JP, Sant'Ana A. A clinical pilot study comparing traditional acupuncture to combined acupuncture for treating headache, trigeminal neuralgia and retro-auricular pain in facial palsy. J Acupunct Meridian Stud. 2011;4:29–43.CrossRefGoogle Scholar
  9. 9.
    Kotlyar A. Treatment of facial pain with I Ching balance acupuncture. Med Acupunct. 2017;29:405–10.CrossRefGoogle Scholar
  10. 10.
    Yameen F, Shahbaz NN, Hasan Y, Fauz R, Abdullah M. Efficacy of transcutaneous electrical nerve stimulation and its different modes in patients with trigeminal neuralgia. J Pak Med Assoc. 2011;61:437–9.PubMedPubMedCentralGoogle Scholar
  11. 11.
    Singla S, Prabhakar V, Singla RK. Role of transcutaneous electric nerve stimulation in the management of trigeminal neuralgia. J Neurosci Rural Pract. 2011;2:150–2.CrossRefGoogle Scholar
  12. 12.
    Uhlemann C, Heinig B, Wollina U. Therapeutic ultrasound in lower extremity wound management. Int J Low Extrem Wounds. 2003;2:152–7.CrossRefGoogle Scholar
  13. 13.
    Adahan HM, Sharon H, Siev-Ner I. A sound solution to tendonitis: healing tendon tears with a novel low-intensity, low-frequency surface acoustic ultrasound patch. PMR. 2010;2:685–7.CrossRefGoogle Scholar
  14. 14.
    Adahan HM, Yacov I, Siev-Ner I, Alexander B. A sound solution for trigeminal neuralgia. (Conference Paper); 7th Congress of the European Federation of IASP Chapters (EFIC) 2011;Vol 3Google Scholar
  15. 15.
    Carmichael A. PA and fish oil. Br Dent J. 2012;212:356–7.CrossRefGoogle Scholar
  16. 16.
    Kapoor S. Vitamin C for attenuating postherpetic neuralgia pain: an emerging treatment alternative. J Headache Pain. 2012;13:591.CrossRefGoogle Scholar
  17. 17.
    Kopruszinski CM, Reis RC, Chichorro JG. B vitamins relieve neuropathic pain behaviours induced by infraorbital nerve constriction in rats. Life Sci. 2012;91:1187–95.CrossRefGoogle Scholar
  18. 18.
    Institute for chronic pain. What is biofeedback? Available at: management/biofeedback. Accessed Jan 10, 2018.
  19. 19.
    Sime ALCSW. Case study of trigeminal neuralgia using neurofeedback and peripheral biofeedback. J Neurother. 2004;8:59–71.CrossRefGoogle Scholar
  20. 20.
    Mojaver YN, Mosavi F, Mazaherinezhad A, Shahrdar A, Manshaee K. Individualized homeopathic treatment of trigeminal neuralgia: an observational study. Homeopathy. 2007;96:82–6.CrossRefGoogle Scholar
  21. 21.
    Zakrzewska JM. Multi-dimensionality of chronic pain of the oral cavity and face. J Headache Pain. 2013;14:37.CrossRefGoogle Scholar
  22. 22.
    Hals EKB, Stubhaug A. Mental and somatic co-morbidities in chronic orofacial pain conditions: pain patients in need of multiprofessional team approach. Scand J Pain. 2011;2:153–4.CrossRefGoogle Scholar
  23. 23.
    Wu TH, Hu LY, Lu T, Chen PM, Chen HJ, Shen CC, et al. Risk of psychiatric disorders following trigeminal neuralgia: a nationwide population-based retrospective cohort study. J Headache Pain. 2015;16:64.CrossRefGoogle Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Rajeeb Kumar Mishra
    • 1
  • Girija Prasad Rath
    • 1
  1. 1.Department of Neuroanaesthesiology and Critical Care Neurosciences CentreAll India Institute of Medical SciencesNew DelhiIndia

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