Neuromodulation in Trigeminal Neuralgia

  • Ritesh Lamsal
  • Girija Prasad Rath


The treatment of classical trigeminal neuralgia (TGN) has traditionally revolved around the use of antiepileptic drugs (AEDs), and surgery in drug-refractory cases. Both techniques have variable degrees of success and recurrence is a common theme in many patients. Further, pharmacotherapy and surgery are not devoid of adverse effects or complications. There are also some studies that show good results with other techniques, like ablative procedures [1] and botulinum injections [2], but there are wide differences in their applications, dosing protocols, long-term efficacy, and overall acceptance across various institutes. Neuromodulation is an exciting prospect that utilizes advanced technologies using electrical or chemical methods, targeting either neural stimulation or inhibition, in order to restore normal neurological function. Neuromodulation techniques to treat TGN is still in its nascent stages, with considerable room to evolve and improve. However, there are promising results from some preliminary studies. A broad classification scheme of various neuromodulation techniques is presented in Table 1.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Ritesh Lamsal
    • 1
  • Girija Prasad Rath
    • 1
  1. 1.Department of Neuroanaesthesiology and Critical Care Neurosciences CentreAll India Institute of Medical SciencesNew DelhiIndia

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