Abstract
The term “personalized medicine” has acquired a new meaning in western medicine based on the relatively recent growth in health, wellness and disease prevention approaches. Traditional practices that emphasized uniform, standardized treatments for illnesses or pathologies en masse have given way as modern genetics revolutionizes disease prevention and wellness for the individual. Ayurveda, however, has emphasized individual, personalized medicine and wellness since its foundation thousands of years ago. Western medicine lacks concepts pertaining to prakriti that recognize a person’s inherent individuality and the doshas, Vata, Pitta, and Kapha, that are the basis for individual behavior, physiology, and spirituality and, hence, the health, wellness, or predisposition to illnesses for each person. Ayurgenetics represents the union of western science with the philosophy of eastern traditional Ayurvedic medicine. From this merger, personalized medicine across many cultures can encompass the philosophy and spirituality of Ayurveda while utilizing modern western science and technology. Application of technologies in genomics, diagnostics, pharmacology and therapeutics in the context of prakriti for western medicine focuses on the individual, representing a new frontier in medicine, health, and wellness. The east welcomes the west to personalized medicine.
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References
Dey S, Pahwa P. Prakriti and its associations with metabolism, chronic diseases, and genotypes: possibilities of new born screening and a lifetime of personalized prevention. J Ayurveda Integr Med. 2014;5(1):15–24. https://doi.org/10.4103/0975-9476.128848.
Prasher B, Gibson G, Mukerji M. Genomic insights into ayurvedic and western approaches to personalized medicine. J Genet. 2016;95(1):209–28. https://doi.org/10.1007/s12041-015-0607-9.
Rastogi S. Building bridges between Ayurveda and modern science. Int J Ayurveda Res. 2010;1(1):41–6. https://doi.org/10.4103/0974-7788.59943.
Gupta D, Pandy A, Kar AC. Concept of Prakriti: an Ayurvedic review. World J Pharm Pharm Sci. 2015;4(9):284–90.
Lad V. Textbook of Ayurveda: fundamental principles. Albuquerque: Ayurvedic Press; 2002.
Gupta PD. Pharmacogenetics, pharmacogenomics and ayurgenomics for personalized medicine: a paradigm shift. Indian J Pharm Sci. 2015;77(2):135–41.
Patwardhan B. Time for evidence-based Ayurveda: a clarion call for action. J Ayurveda Integr Med. 2013;4(2):63–6. https://doi.org/10.4103/0975-9476.113860.
Prasher B, Negi S, Aggarwal S, et al. Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. J Transl Med. 2008;6:48. https://doi.org/10.1186/1479-5876-6-48.
Prasher B, Varma B, Kumar A, et al. Ayurgenomics for stratified medicine: TRISUTRA consortium initiative across ethnically and geographically diverse Indian populations. J Ethnopharmacol. 2017;197(Suppl C):274–93.
Chatterjee B, Pancholi J. Prakriti-based medicine: a step towards personalized medicine. Ayu. 2011;32(2):141–6. https://doi.org/10.4103/0974-8520.92539.
Tripathi YB. Molecular approach to ayurveda. Indian J Exp Biol. 2000;38(5):409–14.
Corcos AF. Reproduction and heredity beliefs of the Hindus based on their sacred books. J Hered. 1984;75(2):152–4.
Aggarwal S, Gheware A, Agrawal A, et al. Combined genetic effects of EGLN1 and VWF modulate thrombotic outcome in hypoxia revealed by Ayurgenomics approach. J Transl Med. 2015;13:9. https://doi.org/10.1186/s12967-015-0542-9.
Bhushan P, Kalpana J, Arvind C. Classification of human population based on HLA gene polymorphism and the concept of Prakriti in Ayurveda. J Altern Complement Med. 2005;11(2):349–53. https://doi.org/10.1089/acm.2005.11.349.
Patwardhan B, Bodeker G. Ayurvedic genomics: establishing a genetic basis for mind-body typologies. J Altern Complement Med. 2008;14(5):571–6. https://doi.org/10.1089/acm.2007.0515.
Rizzo-Sierra CV. Ayurvedic genomics, constitutional psychology, and endocrinology: the missing connection. J Altern Complement Med. 2011;17(5):465–8. https://doi.org/10.1089/acm.2010.0412.
Sethi TP, Prasher B, Mukerji M. Ayurgenomics: a new way of threading molecular variability for stratified medicine. ACS Chem Biol. 2011;6(9):875–80. https://doi.org/10.1021/cb2003016.
Coffin D, Lurie D. Ayurgenetics: East meets West in modern health, wellness, and medicine. Ayurveda J Health. 2016;14(4):17–23.
Lurie D. Ayurveda and pharmacogenomics. Ann Ayurvedic Med. 2012;1(4):126–8.
Khatoon S, Rai V, Rawat AK, et al. Comparative pharmacognostic studies of three Phyllanthus species. J Ethnopharmacol. 2006;104(1–2):79–86. S0378-8741(05)00587-8 [pii].
Rastogi S, Kalra A, Gupta V, et al. Unravelling the genome of Holy basil: an “incomparable” “elixir of life” of traditional Indian medicine. BMC Genomics. 2015;16:413. https://doi.org/10.1186/s12864-015-1640-z.
Charaka Samhita Ayurveda. Charaka Samhita. http://www.charakasamhita.com/. Accessed Nov 2017.
Clark B. Yin Yoga. Yinyoga.com. http://www.yinyoga.com/ys1_4.1.1_purusha_prakriti.php. Accessed Nov 2017.
Ortiz-Ospina E. “Life Expectancy”—what does this actually mean? 2017. www.ourworldindata.org.
Science Squared. Next generation sequencing. Bitesize Bio. 2017. https://bitesizebio.com/21193/a-beginners-guide-to-next-generation-sequencing-ngs-technology/. Accessed Nov 2017.
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Coffin, J.D., Rao, R., Lurie, D.I. (2019). Translational Potential of Ayurveda Prakriti: Concepts in the Area of Personalized Medicine. In: Rastogi, S. (eds) Translational Ayurveda . Springer, Singapore. https://doi.org/10.1007/978-981-13-2062-0_3
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