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Thyroid Cancer Screening Program for Young People in Fukushima After the Nuclear Plant Accident

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Thyroid FNA Cytology

Abstract

The Great East Japan Earthquake of March 11, 2011, caused the Fukushima Daiichi Nuclear Power Station accident, which is regarded as a level 7, major accident, on the International Nuclear and Radiological Event Scale. There was a great concern among the general public in Japan about the various health impacts of this compound nuclear disaster, including rapid changes in the overall lifestyle and dispersion of radioactive material [1]. In particular, radiation-induced thyroid cancers are one of the greatest concerns among local residents after the disaster. To address the health risks, it is necessary to communicate health-related information and establish a system to support residents through health surveillance [2, 3] (see Chap. 12). Although the radiation exposure level in Fukushima has been reported to be much lower than that in Chernobyl [4], conducting surveys is required for both scientific and social demand [5]. Thyroid ultrasound examinations have been conducted as part of the Fukushima Health Management Survey (FHMS) commissioned by Fukushima Prefecture [6, 7]. Along with the advances of ultrasonic imaging diagnostic technology, overdiagnosis has become a global issue in recent decades [8, 9]. Therefore, careful attention must be paid when interpreting screening results [10, 11].

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References

  1. Hasegawa A, Tanigawa K, Ohtsuru A, Yabe H, Maeda M, Shigemura J, Ohira T, Tominaga T, Akashi M, Hirohashi N, Ishikawa T, Kamiya K, Shibuya K, Yamashita S, Chhem RK. Health effects of radiation and other health problems in the aftermath of nuclear accidents, with an emphasis on Fukushima. Lancet. 2015;386:479–88.

    Article  Google Scholar 

  2. Ohtsuru A, Tanigawa K, Kumagai A, Niwa O, Takamura N, Midorikawa S, Nollet K, Yamashita S, Ohto H, Chhem RK, Clarke M. Nuclear disasters and health: lessons learned, challenges, and proposals. Lancet. 2015;386(9992):489–97.

    Article  Google Scholar 

  3. SHAMISEN Project. Nuclear Emergency Situations Improvement of Medical and Health Surveillance. http://www.eu-neris.net/index.php/projects/operra/project-operra-shamisen.html. Accessed 28 Dec 2017.

  4. United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and effects of ionizing radiation. UNSCEAR 2013 Report Volume I. Report to the General Assembly. Scientific annexes A: levels and effects of radiation exposure due to the nuclear accident after the 2011 Great East-Japan earthquake and tsunami. New York: United Nations; 2013.

    Google Scholar 

  5. Yamashita S, Suzuki S. Risk of thyroid cancer after the Fukushima nuclear power plant accident. Respir Invest. 2013;51:128–33.

    Article  Google Scholar 

  6. Yasumura S, Hosoya M, Yamashita S, Kamiya K, Abe M, Akashi M, Kodama K, Ozasa K, the Fukushima Health Management Survey Group. Study protocol for the Fukushima health management survey. J Epidemiol. 2012;22:375–83.

    Article  Google Scholar 

  7. Yamashita S. Tenth Warren, K Memorial Sinclair keynote address—the Fukushima nuclear power plant accident and comprehensive health risk management. Health Phys. 2014;106:166–80.

    Article  CAS  Google Scholar 

  8. Bibbins-Domingo K, Grossman DC, Curry SJ, et al. Screening for thyroid cancer: US preventive services task force recommendation statement. JAMA. 2017;317(18):1882–7.

    Article  Google Scholar 

  9. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, Pacini F, Randolph GW, Sawka AM, Schlumberger M, Schuff KG, Sherman SI, Sosa JA, Steward DL, Tuttle RM, Wartofsky L. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016;26:1–133.

    Article  Google Scholar 

  10. Katanoda K, Kamo K, Tsugane S. Quantification of the increase in thyroid cancer prevalence in Fukushima after the nuclear disaster in 2011--a potential overdiagnosis? Jpn J Clin Oncol. 2016;46(3):284–6.

    Article  Google Scholar 

  11. Takahashi H, Takahashi K, Shimura H, Yasumura S, Suzuki S, Ohtsuru A, Midorikawa S, Ohira T, Ohto H, Yamashita S, Kamiya K. Simulation of expected childhood and adolescent thyroid cancer cases in Japan using a cancer-progression model based on the National Cancer Registry: application to the first-round thyroid examination of the Fukushima health management survey. Medicine (Baltimore). 2017;96(48):e8631.

    Article  Google Scholar 

  12. Suzuki S, Yamashita S, Fukushima T, Nakano K, Midorikawa S, Ohtsuru A, Yasumura S, Hosoya M, Kamiya K, Shimura H, Suzuki S. The protocol and preliminary baseline survey results of the thyroid ultrasound examination in Fukushima [rapid communication]. Endocr J. 2016a;63(3):315–21.

    Article  CAS  Google Scholar 

  13. Midorikawa S, Tanigawa K, Suzuki S, Ohtsuru A. Psychosocial issues related to thyroid examination after a radiation disaster. Asia Pac J Public Health. 2017;29(2_suppl):63S–73S.

    Article  Google Scholar 

  14. Suzuki S, Suzuki S, Fukushima T, Midorikawa S, Shimura H, Matsuzuka T, Ishikawa T, Takahashi H, Ohtsuru A, Sakai A, Hosoya M, Yasumura S, Nollet KE, Ohira T, Ohto H, Abe M, Kamiya K, Yamashita S. Comprehensive survey results of childhood thyroid ultrasound examinations in Fukushima in the first four years after the Fukushima Daiichi nuclear power plant accident. Thyroid. 2016b;26(6):843–51.

    Article  Google Scholar 

  15. Proceeding of the 27th Prefectural Oversight Committee Meeting for the Fukushima Health Management Survey. http://fmu-global.jp/proceedings-of-the-27th-prefectural-oversight-committee-meeting/. Accessed 28 Dec 2017.

  16. Büyükyavuz I, Otçu S, Karnak I, Akçören Z, Senocak ME. Ectopic thymic tissue as a rare and confusing entity. Eur J Pediatr Surg. 2002;12:327–9.

    Article  Google Scholar 

  17. Durmaz E, Barsal E, Parlak M, Gurer I, Karaguzel G, Akcurin S, Bircan I. Intrathyroidal ectopic thymic tissue may mimic thyroid cancer: a case report. J Pediatr Endocrinol Metab. 2012;25:997–1000.

    PubMed  Google Scholar 

  18. Lignitz S, Musholt TJ, Kreft A, Engel R, Brzezinska R, Pohlenz J. Intrathyroidal thymic tissue surrounding an intrathyroidal parathyroid gland, the cause of a solitary thyroid nodule in a 6-year-old boy. Thyroid. 2008;18:1125–30.

    Article  Google Scholar 

  19. Fukushima T, Suzuki S, Ohira T, Shimura H, Midorikawa S, Ohtsuru A, Sakai A, Abe M, Yamashita S, Suzuki S. Prevalence of ectopic intrathyroidal thymus in Japan: the Fukushima health management survey. Thyroid. 2015;25(5):534–7.

    Article  Google Scholar 

  20. Takamura N, Orita M, Saenko V, Yamashita S, Nagataki S, Demidchik Y. Radiation and risk of thyroid cancer: Fukushima and Chernobyl. Lancet Diabetes Endocrinol. 2016;4(8):647.

    Article  Google Scholar 

  21. Williams D. Thyroid growth and cancer. Eur Thyroid J. 2015;4:164–73.

    Article  CAS  Google Scholar 

  22. Wilson JMG, Jonner G. Principles and practice of screening for disease. Geneva: World Health Organization; 1968.

    Google Scholar 

  23. Takano T. Natural history of thyroid cancer. Endocr J. 2017;64(3):237–44.

    Article  Google Scholar 

  24. Ahn HS, Kim HJ, Welch HG. Korea’s thyroid-cancer “epidemic”—screening and overdiagnosis. N Engl J Med. 2014;371(19):1765–7.

    Article  Google Scholar 

  25. Vaccarella S, Franceschi S, Bray F, Wild CP, Plummer MI, Dal Maso L. Worldwide thyroid-cancer epidemic? The increasing impact of overdiagnosis. N Engl J Med. 2016;375(7):614–7.

    Article  Google Scholar 

  26. Midorikawa S, Ohtsuru A, Murakami M, et al. Comparative analysis of the growth pattern of thyroid cancer in young patients screened by ultrasonography in Japan after a nuclear accident. The Fukushima Health Management Survey. JAMA Otolaryngol Head Neck Surg. 2018;144(1):57–63.

    PubMed  Google Scholar 

  27. Meinhold CL, Ron E, Schonfeld SJ, Alexander BH, Freedman DM, Linet MS, Berrington de González A. Nonradiation risk factors for thyroid cancer in the US Radiologic Technologists Study. Am J Epidemiol. 2010;171(2):242–52.

    Article  Google Scholar 

  28. United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and effects of ionizing radiation: UNSCEAR 2008 report to the general assembly with scientific annexes. New York: United Nations; 2010.

    Google Scholar 

  29. Nagataki S, Takamura N. Radioactive doses—predicted and actual— and likely health effects. Clin Oncol (R Coll Radiol). 2016;28:245–54.

    Article  CAS  Google Scholar 

  30. Tokonami S, Hosoda M, Akiba S, Sorimachi A, Kashiwakura I, Balonov M. Thyroid doses for evacuees from the Fukushima nuclear accident. Sci Rep. 2012;2:507.

    Article  Google Scholar 

  31. Matsuda N, Kumagai A, Ohtsuru A, Morita N, Miura M, Yoshida M, Kudo T, Takamura N, Yamashita S. Assessment of internal exposure doses in Fukushima by a whole body counter within one month after the nuclear power plant accident. Radiat Res. 2013;179(6):663–8.

    Article  CAS  Google Scholar 

  32. Ishikawa T, Yasumura S, Ozasa K, Kobashi G, Yasuda H, Miyazaki M, Akahane K, Yonai S, Ohtsuru A, Sakai A, Sakata R, Kamiya K, Abe M. The Fukushima health management survey: estimation of external doses to residents in Fukushima prefecture. Sci Rep. 2015;5:12712.

    Article  CAS  Google Scholar 

  33. Welch HG, Black WC. Overdiagnosis in cancer. J Natl Cancer Inst. 2010;102:605–13.

    Article  Google Scholar 

  34. Ohtsuru A, Midorikawa S, Suzuki S, Shimura H, Matsuzuka T, Yamashita S. Five-year interim report of thyroid ultrasound examinations in the Fukushima Health Management Survey. In: Yamashia S, Thomas G, editors. Thyroid cancer and nuclear accidents: long-term after-effects of Chernobyl and Fukushima. 1st ed. Cambridge: Academic Press; 2017.

    Google Scholar 

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Correspondence to Akira Ohtsuru .

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Ohtsuru, A., Midorikawa, S., Suzuki, S., Shimura, H., Matsuzuka, T., Yamashita, S. (2019). Thyroid Cancer Screening Program for Young People in Fukushima After the Nuclear Plant Accident. In: Kakudo, K. (eds) Thyroid FNA Cytology. Springer, Singapore. https://doi.org/10.1007/978-981-13-1897-9_68

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  • DOI: https://doi.org/10.1007/978-981-13-1897-9_68

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