Biomimetic Scaffolds for Bone Tissue Engineering

  • Joon Yeong Park
  • Seung Hun Park
  • Mal Geum Kim
  • Sang-Hyug Park
  • Tae Hyeon Yoo
  • Moon Suk KimEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1064)


The use of biomimetic scaffolds for bone tissue engineering has been studied for a long time. Biomimetic scaffolds can assist and accelerate bone regeneration that is similar to that of authentic tissue, which represents the environment of cells in a living organism. Currently, numerous biomaterials have been reported for use as a biomimetic scaffold. This review focuses on the design of biomimetic scaffolds, kinds of biomaterials and methods used to fabricate biomimetic scaffolds, growth factors used with biomimetic scaffold for bone regeneration, mobilization of biological agents into biomimetic scaffolds, and studies on (pre)clinical bone regeneration from biomimetic scaffolds. Then, future prospects for biomimetic scaffolds are discussed.


Biomimetic scaffold Biomaterial Bone regeneration Tissue engineering 



This work was supported by a grant from a Basic Science Research Program (2016R1A2B3007448) and Priority Research Centers Program (2010-0028294) through the National Research Foundation of Korea (NRF) funded by the Ministry of Education.

Conflicts of Interest

The authors declare no conflict of interest.


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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Joon Yeong Park
    • 1
  • Seung Hun Park
    • 1
  • Mal Geum Kim
    • 1
  • Sang-Hyug Park
    • 2
  • Tae Hyeon Yoo
    • 1
  • Moon Suk Kim
    • 1
    Email author
  1. 1.Department of Molecular Science and TechnologyAjou UniversitySuwonSouth Korea
  2. 2.Department of Biomedical EngineeringPukyong National UniversityBusanSouth Korea

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