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World Congress on Medical Physics and Biomedical Engineering 2018 pp 235–238Cite as

ApOtEl: Development of a Software for Electroporation Based Therapy Planning

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Part of the book series: IFMBE Proceedings ((IFMBE,volume 68/3))

Abstract

The objective of this paper is to describe the implementation of a software application, called ApOtEl, developed for needle electrodes positioning optimization for electrochemotherapy procedures in the treatment of cutaneous and subcutaneous tumors. The software was developed using MATLAB®, and it optimizes the needle-type electrodes positioning configurations, through the study of the analytical electric field, using Laplace equation in a homogeneous bi-dimensional environment. The optimization was based on requirements chosen to guarantee the tumor total coverage and to minimize healthy neighboring tissues damage. An optimization function was created to orientate the electrochemotherapy application, and the best option available in all configurations generated by the distance variations between electrodes and positioning orientations was determined. The software provides, by the entry of tumor dimensions, the optimized distances for positioning needle-type electrodes, as well as the representation of the electric field distribution and intensity. Representation of the electrodes positioning and instructions for the procedure to facilitate the procedure planning are provided.

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References

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Compliance with ethical standards

Conflicts of interest: The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Electrical Engineering Graduate Program, PUCRS, Porto Alegre, Brazil

    Luisa Endres Ribeiro da Silva & Ana Maria Marques da Silva

  2. State Electrical Energy Company, CEEE, Porto Alegre, Brazil

    Marcos Tello

  3. Laboratory of Medical Imaging, Science School, PUCRS, Porto Alegre, Brazil

    Dario F. G. de Azevedo & Ana Maria Marques da Silva

Authors
  1. Luisa Endres Ribeiro da Silva
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  2. Marcos Tello
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  3. Dario F. G. de Azevedo
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  4. Ana Maria Marques da Silva
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Corresponding author

Correspondence to Luisa Endres Ribeiro da Silva .

Editor information

Editors and Affiliations

  1. CIIRC, Czech Technical University in Prague, Prague, Czech Republic

    Lenka Lhotska

  2. Institute of Clinical and Experimental Medicine, Prague, Czech Republic

    Lucie Sukupova

  3. Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia

    Igor Lacković

  4. Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

    Geoffrey S. Ibbott

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© 2019 Springer Nature Singapore Pte Ltd.

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da Silva, L.E.R., Tello, M., de Azevedo, D.F.G., da Silva, A.M.M. (2019). ApOtEl: Development of a Software for Electroporation Based Therapy Planning. In: Lhotska, L., Sukupova, L., Lacković, I., Ibbott, G. (eds) World Congress on Medical Physics and Biomedical Engineering 2018. IFMBE Proceedings, vol 68/3. Springer, Singapore. https://doi.org/10.1007/978-981-10-9023-3_42

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  • DOI: https://doi.org/10.1007/978-981-10-9023-3_42

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-10-9022-6

  • Online ISBN: 978-981-10-9023-3

  • eBook Packages: EngineeringEngineering (R0)

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