Immuno-Chemotherapeutic Platinum(IV) Prodrugs of Cisplatin as Multimodal Anticancer Agents

  • Daniel Yuan Qiang WongEmail author
Part of the Springer Theses book series (Springer Theses)


For the longest time, the contribution of the immune system in chemotherapy has been disregarded as cytotoxic drugs are generally believed to be immunosuppressive [1, 2, 3, 4, 5]. Consequently, evaluation of new chemotherapeutic agents involved screening of drug candidates upon xenografted tumors in immunodeficient mice which neglects any possible immune contribution.


WKYMVm Positive Control Cisplatin Complete DMEM Hydrophilic Interaction Liquid Chromatography Analysis Drug Conjugates 
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Supplementary material


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© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of ChemistryNational University of SingaporeSingaporeSingapore

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