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Cardiovascular Engineering pp 201–218Cite as

Computational Fluid Dynamics Application in Reducing Complications of Patent Ductus Arteriosus Stenting

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Part of the book series: Series in BioEngineering ((SERBIOENG))

Abstract

In some cases, especially in neonates, ductus arteriosus needs to remain patent for multiple medical purposes. In order to achieve this, current practice involves inserting stent in the ductus arteriosus. This condition is called patent ductus arteriosus (PDA). For this process, stents such as coronary stent are commonly used due to unavailability of customized stent for PDA in neonates. The usage of coronary stent however, opens the possibility of acute stent thrombosis and other complications. Therefore, there is a high need of special and customized stents to be used for PDA in neonates. This customized stent has to be able to sustain the hemodynamic effects of the flow inside the PDA. The stent has to be able to support the ductus wall compression and contraction due to arterial compliance. What is more important is that the stent must properly fit into various morphologies of the ductus. There are several different morphologies of PDA identified and the stents must be able to sustain the various shapes and tortuosity. In addition, the stent has to be tested for biocompatibility and practicality. Therefore, the customized design of the PDA stents can be derived from the concept of coronary stents and in compliance with all the mentioned characteristics. However, further analysis has to be completed ensure proper compatibility with neonates. In conclusion, the biggest challenge is to customize a stent that fits all the PDA morphologies.

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Acknowledgments

The support of the University of Teknologi Malaysia, under the Ministry of Education Malaysia and IJN-UTM Cardiovascular Centre grant, led by Dr. Kahar Osman under grant number 4F240, 01G77, 01G17 and 4L638 are gratefully acknowledged.

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Authors and Affiliations

  1. Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, 81310, Skudai, Johor, Malaysia

    M. I. Kori, K. Osman & A. Z. M. Khudzari

  2. IJN-UTM Cardiovascular Engineering Centre, Institute of Human Centered Engineering, Universiti Teknologi Malaysia, 81310, Skudai, Johor, Malaysia

    K. Osman & A. Z. M. Khudzari

  3. Faculty Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Parit Raja, Johor, Malaysia

    I. Taib

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Editors and Affiliations

  1. School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia

    Dyah Ekashanti Octorina Dewi

  2. School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia

    Yuan Wen Hau

  3. School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia

    Ahmad Zahran Mohd Khudzari

  4. School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia

    Ida Idayu Muhamad

  5. School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru, Johor, Malaysia

    Eko Supriyanto

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Kori, M.I., Osman, K., Khudzari, A.Z.M., Taib, I. (2020). Computational Fluid Dynamics Application in Reducing Complications of Patent Ductus Arteriosus Stenting. In: Dewi, D., Hau, Y., Khudzari, A., Muhamad, I., Supriyanto, E. (eds) Cardiovascular Engineering. Series in BioEngineering. Springer, Singapore. https://doi.org/10.1007/978-981-10-8405-8_9

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  • DOI: https://doi.org/10.1007/978-981-10-8405-8_9

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