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Recent Advances in Triazolyl Nucleosides

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Green Chemistry in Environmental Sustainability and Chemical Education

Abstract

Nucleosides and its modified analogues are important components and possess key roles in various biological processes. Copper catalyzed 1,3-dipolar cycloadditions have been emerged as an excellent tool to join azide and alkyne moieties to form triazolyl compounds. Presence of triazole group enhances the therapeutic potential as well as fluorescence properties of the modified nucleosides. Owing to the designing and development of the new triazolyl nucleosides for their various biological and photophysical application at faster pace, there is a need to have knowledge of the recent developments in this area. The review herein highlights the various modifications, therapeutic importance and other applications of recently reported triazolyl-nucleosides.

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Authors and Affiliations

  1. Department of Chemistry, University of Delhi, New Delhi, 110007, Delhi, India

    Smriti Srivastava, Vipin K. Maikhuri & Ashok K. Prasad

  2. Department of Chemistry, Daulat Ram College, University of Delhi, Delhi, 110007, India

    Divya Mathur

Authors
  1. Smriti Srivastava
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  2. Vipin K. Maikhuri
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  3. Divya Mathur
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  4. Ashok K. Prasad
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Correspondence to Ashok K. Prasad .

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Editors and Affiliations

  1. Institute of Advanced Sciences, Dartmouth, Massachusetts, USA

    Virinder S. Parmar

  2. Department of Chemistry, Daulat Ram College, University of Delhi, Delhi, India

    Priti Malhotra

  3. Department of Chemistry, Daulat Ram College, University of Delhi, Delhi, India

    Divya Mathur

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Srivastava, S., Maikhuri, V.K., Mathur, D., Prasad, A.K. (2018). Recent Advances in Triazolyl Nucleosides. In: Parmar, V., Malhotra, P., Mathur, D. (eds) Green Chemistry in Environmental Sustainability and Chemical Education. Springer, Singapore. https://doi.org/10.1007/978-981-10-8390-7_16

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