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Anticancer Plants: Clinical Trials and Nanotechnology pp 153–180Cite as

Designing of Natural Anticancerous Drugs and Their Delivery System

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Abstract

Chemoprevention of cancer with conventional therapeutic approach has shown severe side effects along with high possibility of recurrence of the same. This results in decreased therapeutic efficacy of the chemotherapeutic agents used currently. Therefore, to reduce their ill effects, an alternative gateway for cancer treatment and prevention needs to be explored. The natural, plant-based anticancer compounds are proving to be a substantial target in replacing the common approaches which employs chemical drugs. The natural compounds derived from various medicinal plants like vinca alkaloids, cyanidin, curcumin, fisetin, rosmarinic acid, etc. have already been documented with a remarkable antineoplastic property. The aim of the chapter is to focus on the various phytocompounds and their mechanism of action to treat the tumorigenic growth accompanied with the drug delivery system. Furthermore, the limitations and barriers associated with the formulation of phytocompounds and their possible enhanced therapeutic efficiency by nanoparticle-based drug delivery mechanics are also discussed.

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Authors and Affiliations

  1. Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

    Manisha Singh, Rashi Rajput, Ramneek Kaur, Sachin Kumar &  Rachana

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  1. Manisha Singh
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  2. Rashi Rajput
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  3. Ramneek Kaur
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  4. Sachin Kumar
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  5. Rachana
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  1. Department of Botany, Gandhi Faiz-e-Aam College, Shahjahanpur, Uttar Pradesh, India

    Mohd Sayeed Akhtar

  2. Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia, Serdang, Selangor, Malaysia

    Mallappa Kumara Swamy

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Singh, M., Rajput, R., Kaur, R., Kumar, S., Rachana (2017). Designing of Natural Anticancerous Drugs and Their Delivery System. In: Akhtar, M., Swamy, M. (eds) Anticancer Plants: Clinical Trials and Nanotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-10-8216-0_5

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