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Scopolamine

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Natural Small Molecule Drugs from Plants

Abstract

Scopolamine is a type of alkaloid from a variety of Solanaceae plants, which is the main active ingredient of these plants. It was first isolated from the Scopolia japonica, so named as scopolamine. Due to its obvious deficiencies in solubility and usage, its structure was modified as scopolamine butylbromide, which is widely used in clinical for the treatment of gastrointestinal motility hyperthyroidism or cramps, biliary colic, renal colic, and so on. With the deeper understanding of this drug, clinical application will be given more scientific and reasonable guidance.

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Authors and Affiliations

  1. Beijing Key Laboratory of Drug Targets, Research and Drug Screening, National Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Lv-Jie Xu, Ai-Lin Liu & Guan-Hua Du

Authors
  1. Lv-Jie Xu
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  2. Ai-Lin Liu
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  3. Guan-Hua Du
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Correspondence to Ai-Lin Liu or Guan-Hua Du .

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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China

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Xu, LJ., Liu, AL., Du, GH. (2018). Scopolamine. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_53

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