Abstract
Rotundine is a kind of organic alkaloid with analgesic activity extracted from traditional Chinese medicinal plant named Corydalis rhizoma. It has been used in a lot of countries as an alternative to anxiolytic and sedative drugs of the benzodiazepine group and analgesics such as opiates. Rotundine has potent effects on the central nervous system but has nothing to do with opioid receptors. Therefore, it has little addiction effects. Recent studies also found other pharmacology effects of Rotundine, such as cardiovascular protective effects and antitumor effects. Because of its low toxicity and less adverse reactions, Rotundine has attracted a lot of attention in pain management. It has great market prospects and deserves further development and utilization.
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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China
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Yuan, TY., Du, LD., Du, GH. (2018). Rotundine. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_52
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DOI: https://doi.org/10.1007/978-981-10-8022-7_52
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