• Jia-Lin Sun
  • Li-Da Du
  • Guan-Hua DuEmail author


Chelidonine, also named ranunculine, is a benzophenanthridine alkaloid isolated from the whole plant of Chelidonium majus. L. It has been used as a painkiller in clinical treatment based on its morphine-like analgesic effect. Pharmacological researches in recent years have demonstrated that chelidonine played a role in antitumor, antibacterial, spasmolysis activities, and so on. And the antitumor activity is drawing more and more attention. However, its mechanisms of function remain unclear, which needs to be clarified in the future.


Chelidonium majus.Chelidonine Analgesia Antitumor 


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© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2018

Authors and Affiliations

  1. 1.Department of PharmacyThe Affiliated Hospital of Qingdao UniversityQingdaoChina
  2. 2.School of Biomedical SciencesChinese University of Hong KongHong KongChina
  3. 3.Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

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