Caffeic acid is used for preventing or stopping bleeding during surgery, as well as hemostasis in the departments of medicine, obstetrics, gynecology, etc. It has a wide range of pharmacological effects, including inhibition of platelet aggregation, anti-inflammatory and antioxidant effects, and immune regulation, and it is also an important pharmaceutical product and pharmaceutical intermediate. These make caffeic acid a focus, and scientists are committed to its structural modification trying to find small molecules with better activity for the treatment of oxidative stress-related diseases.
KeywordsCaffeic acid Solidaginis herba Hemostasis
- 1.Wang Y. Analysis of pharmacological action of Solidago canadensis. Chin J Ethnomedicine Ethnopharmacy. 2016;16:150.Google Scholar
- 2.Macheix JJ, Fleuriet A, Billot J. Fruit phenolic. Boca Raton: CRC Press; 1990.Google Scholar
- 3.Xin Z, Zhang L. The synthesis study of caffeic acid. Shandong Chem Ind. 2014;43(3):39–43.Google Scholar
- 11.Li P, Li Q. Anti-angina pectoris active ingredient–protocatechuic aldehyde. Chem World. 1991;7:334–5.Google Scholar
- 12.Wu L. New hemostatic and leukopenic–caffeic acid and caffeine amines. J Nanjing Ins Pharm. 1980;2:24.Google Scholar