• Hui-Fang Zhang
  • Lian-Hua Fang
  • Guan-Hua DuEmail author


Amisodamine is a kind of alkaloid, which abstracted from anisodus tanguticus. It is a kind of traditional Chinese medicine and used to the treatment of pain. Beijing friendship hospital is the first one use it in clinical practice. With the progress made in clinical reaearch, a lot of pharmacology effects were found, such as cholinolytic effect, calcium antagonist effect, anti-oxygenation effect.


Amisodamine Traditional Chinese medicine Pharmacology effects 


  1. 1.
    Mei RB, Wang BG, Wang MG. Inhibitory action of aninsodamine on choilnergic transmission of toad sympathetic ganglion in vitro. Chin Pharmacol Bull. 1996;12(5):453–5.Google Scholar
  2. 2.
    Liu XC, Tang WX. An experimental study of the anisodamini hydrobromidum treating rabbit ischemic acute renal failure. Chin J Crit Care Med. 1999;12(6):360–1.Google Scholar
  3. 3.
    Yang GD, Zhou WH, Wang X. Effect of Anisodamine on the fluidity of erythroyte membrane and the intrinsic fluorescence of ghost. Chin J Mod Appl Pharm. 1993;10(1):4–6.Google Scholar
  4. 4.
    Sun J, Yao XJ, Zhao DH. Inhibitory effects of anisodamine on lipopolysaccharides attaching to endothelium and inducing NO release. J Fourth Mil Med Univ. 2001;22(12):1082–4.Google Scholar
  5. 5.
    Tang ZX, Wang XY, Gao H. Changes of nitric oxide metabolism and effects of Anisodamine during Endotoxic shock of goats. Chin J Vet Sci. 1991;19(1):69–72.Google Scholar
  6. 6.
    Esberg LB, Ren J. The oxygen radical generator pyrogallol impairs cardiomyocyte contractile function via a superoxide and p38MAP kinase-depengdent pathway: protection by anisodamine and tetramethypyrazine. Cardiovasc Toxicol. 2004;4(4):375–84.CrossRefGoogle Scholar
  7. 7.
    Fu XH, Fan WZ, Gu XS, et al. Effect of intracoronary administration of Anisodamine on slow reflow phenomenon following primary percutaneous coronary intervention in patients with acute myocardial infatction. Natl Med J China. 2007;120(14):1226–31.Google Scholar
  8. 8.
    He ZY, Kong J. Effect of anisodamine on bronchial asthma. J Clin Exp Med. 2008;7(1):63.Google Scholar
  9. 9.
    Yang B, Yan CM. Anisodamine hydrochloride infection to reduce gastrointestinal reaction of erythromycin, 132 case of clinical analysis. J Ningxia Med Coll. 2006;28(6):534–5.Google Scholar

Copyright information

© Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China 2018

Authors and Affiliations

  1. 1.Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Personalised recommendations