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Toosendanin

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Natural Small Molecule Drugs from Plants

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Abstract

Fructus Meliae Toosendan is a traditional Chinese medicine which is still used in internal medicine. Toosendanin is a tetracyclic triterpene compound extracted from fructus toosendan. The structure was identified in 1975. A synthetic strategy is put forth in 2009. It is an ascaridole agent and showed anti-botulinum, antibacterial, anticancer, and anti-inflammatory effects. It is also a neuromuscular blocking agent.

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Author information

Authors and Affiliations

  1. Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

    Rui Zhao

  2. School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China

    Li-Da Du

  3. Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Guan-Hua Du

Authors
  1. Rui Zhao
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  2. Li-Da Du
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  3. Guan-Hua Du
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Corresponding author

Correspondence to Guan-Hua Du .

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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China

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Zhao, R., Du, LD., Du, GH. (2018). Toosendanin. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_120

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