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Sandwich Assays Based on SPR, SERS, GMR, QCM, Microcantilever, SAW, and RRS Techniques for Protein Detection

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Book cover Biosensors Based on Sandwich Assays

Abstract

Among the methods developed for protein sandwich assays, the strategies based on fluorescence, electrochemistry, and color change occupy the predominant portion. However, besides these three major types, there are some other techniques, such as use of surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS), giant magnetoresistive (GMR), quartz crystal microbalance (QCM), microcantilever, surface acoustic wave (SAW), and resonance Rayleigh scattering (RRS), which also play a very important role in the development of the sandwich assay for protein detection. Through integrating different recognition molecules, such as antibodies and aptamers, with conventional or new immerging sensing platforms, these assays exhibit excellent comparable sensitivities and specificities and attract extensive attention. Thus, in this chapter, some recent advances in these fields are summarized and concluding remarks on parts of which should be improved as well as outlook are outlined.

The original version of this chapter was revised: Foreword has been included and authors’ affiliations have been updated. The erratum to this chapter is available at https://doi.org/10.1007/978-981-10-7835-4_13

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Authors and Affiliations

  1. Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan, 430074, People’s Republic of China

    Shenshan Zhan, Xiaoding Lou & Fan Xia

  2. Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Material Science and Chemistry, China University of Geosciences, Wuhan, 430074, People’s Republic of China

    Xiaoding Lou & Fan Xia

  3. School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, People’s Republic of China

    Pei Zhou

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  1. Shenshan Zhan
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  2. Xiaoding Lou
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  3. Pei Zhou
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  4. Fan Xia
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Correspondence to Xiaoding Lou .

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Editors and Affiliations

  1. Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, Hubei, China

    Fan Xia

  2. Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, Hubei, China

    Xiaojin Zhang

  3. Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, Hubei, China

    Xiaoding Lou

  4. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, China

    Quan Yuan

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Zhan, S., Lou, X., Zhou, P., Xia, F. (2018). Sandwich Assays Based on SPR, SERS, GMR, QCM, Microcantilever, SAW, and RRS Techniques for Protein Detection. In: Xia, F., Zhang, X., Lou, X., Yuan, Q. (eds) Biosensors Based on Sandwich Assays. Springer, Singapore. https://doi.org/10.1007/978-981-10-7835-4_5

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