Effects of Oral Glutathione Precursors’ Supplementation on Human Glutathione Level

  • Asdani Saifullah Dolbashid
  • Mas Sahidayana MohktarEmail author
  • Wan Safwani Wan Kamarul Zaman
  • Nur Rasyidah Hasan Basri
  • Mohd Faiz Azmi
  • Sakunie Sawai
  • Mohd Yusof Hasif Ilyasa
Conference paper
Part of the IFMBE Proceedings book series (IFMBE, volume 67)


Glutathione (GSH) is a tripeptide of cysteine, glutamate, and glycine. These amino acids made the synthesis of GSH possible and act as a major cellular antioxidant in the body. The production of GSH in the body depends on several factors; such as dietary intake and cysteine availability. With the turnover rate of endogenous GSH can be as high as 65% per day, more consumers has turned to GSH supplement to maintain or boost up their GSH level. GSH supplement available in the market usually contains GSH precursor/s that are said to be able to increase GSH level in the body. In this study, the oral GSH supplement used contains all three precursors of GSH; cystine replacing cysteine, glutamate, and glycine. Subjects were asked to consume the supplement according to the instructed dosage in order to measure the effects of oral GSH precursors’ supplement on human GSH level after the three-month study period ends. The results from this study suggest that the oral GSH precursors’ supplement increases GSH level across the test groups after the three-month study period.


Glutathione Antioxidant Supplement 



This research was supported and funded by Chakra We Care Resources Sdn Bhd, Project No. PV004-2017.


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Copyright information

© Springer Science+Business Media Singapore 2018

Authors and Affiliations

  • Asdani Saifullah Dolbashid
    • 1
  • Mas Sahidayana Mohktar
    • 1
    • 2
    Email author
  • Wan Safwani Wan Kamarul Zaman
    • 1
    • 2
  • Nur Rasyidah Hasan Basri
    • 1
  • Mohd Faiz Azmi
    • 1
  • Sakunie Sawai
    • 1
  • Mohd Yusof Hasif Ilyasa
    • 3
  1. 1.Department of Biomedical Engineering, Faculty of EngineeringUniversity of MalayaKuala LumpurMalaysia
  2. 2.Faculty of EngineeringCenter for Innovation in Medical Engineering, University of MalayaKuala LumpurMalaysia
  3. 3.Chakra We Care Resources Sdn BhdPetaling JayaMalaysia

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