Cytoreductive Surgery for Peritoneal Metastases: Principles and Techniques

  • Aditi Bhatt
  • Sanket Mehta


The technique of cytoreductive surgery (CRS) was first formally described by Paul Sugarbaker. It is a complex surgical procedure comprising of peritonectomies and visceral resections. Since the first publication about 25 years ago, various aspects of the procedure have been described in greater detail, and some techniques have been modified and refined by other surgeons as well. Training at an expert center is the best way to understand and learn this procedure; however, each surgeon in their practice faces difficult situations while on the learning curve and even thereafter. This chapter provides a comprehensive overview of the rationale, techniques, and patient selection for CRS published in literature. A careful study of the published experiences of experts can guide surgeons on what to resect, how much, how, when, in whom, and how to manage the patient thereafter. A knowledge of the pathophysiology of peritoneal cancer spread forms the basis of providing this treatment and developing innovative therapies for future use.


Peritoneal metastases Cytoreductive surgery Peritonectomy Visceral resection Multi-organ resection Pathophysiology 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  1. 1.Department of Surgical OncologyFortis HospitalBangaloreIndia
  2. 2.Department of Peritoneal Surface OncologySaifee HospitalMumbaiIndia

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