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Lesion Volume Estimation from TBI–MRI

  • O. V. Sanjay Sarma
  • Martha Betancur
  • Ramana Pidaparti
  • L. Karumbaiah
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 563)

Abstract

Traumatic brain injury (TBI) is a major problem affecting millions of people around the world every year. Usually, TBI results from any direct or indirect physical impact, sudden jerks, or blunt impacts to the head, leading to damage to the brain. Current research in TBI is focused on analyzing the biological and behavioral states of patients prone to such injuries. This paper presents a technique applied on MRI images in estimation of lesion volumes in brain tissues of traumatic brain-injured laboratory rats that were subjected to controlled cortical impacts. The lesion region in the brain tissue is estimated using segmentation of the brain, diffusion, and the damage regions. After the segmentation, the area of the damaged portion is estimated across each slice of MRI and the combined volume of damage is estimated through 3D reconstruction.

Keywords

Traumatic brain injury Controlled cortical impact (CCI) Magnetic resonance imaging (MRI) Image segmentation 

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • O. V. Sanjay Sarma
    • 1
  • Martha Betancur
    • 2
  • Ramana Pidaparti
    • 1
  • L. Karumbaiah
    • 2
  1. 1.College of EngineeringUniversity of GeorgiaAthensUSA
  2. 2.Regenerative Bioscience Center, The University of GeorgiaAthensUSA

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