Abstract
The primary aim of radiotherapy in treating cancers is “to achieve maximum possible tumour remission with minimum possible side effects”. This is decided by tumour staging, patient’s performance status as well as other factors like availability of options, financial implications and socioreligious factors. Sometimes achieving maximal dose to tumour tissue with complete sparing of surrounding normal tissue may not always be achievable, and compromises may need to be done. When a patient first presents, the clinician must recognize initial signs or symptoms which might suggest towards a diagnosis of an underlying malignancy. A good clinical examination gives the clinician a good indication of the possible diagnosis and enables him to selectively focus examination more thoroughly. The next step is confirming the presence and type of malignancy and assessing the stage. Staging describes the extent or spread of the disease at the time of diagnosis and is essential in determining the choice of therapy and in assessing prognosis. Treatments for cancer are either curative or palliative, and many factors decide what treatment is offered to the patient like stage of the disease, patient age, performance status of the patient or prognostic features.
References
Denoix P. TNM classification. Bull Inst Nat Hyg (Paris). 1944;1:1.
World Health Organisation. International classification of diseases for oncology. 2nd ed. Geneva: World Health Organisation; 1999.
AJCC cancer staging manual. 7th ed. Philadelphia: Lippincott-Raven Publishers; 2007.
International Union against cancer: TNM classification of malignant tumours. 5th ed. Berlin: Springer; 1997.
Rubin P. Clinical oncology: a multidisciplinary approach for physicians and students. 8th ed. Philadelphia: WB Saunders Publishers; 2001. p. 20.
Tucker R, Coel M, Ko J, et al. Impact of fluorine-18 fluorodeoxyglucose positron emission tomography on patient management: first years’ experience in a clinical centre. J Clin Oncol. 2001;19:2504–8.
Schoder H, Meta J, Yap C, et al. Effect of whole body 18-F FDG PET imaging on clinical staging and management of patients with malignant lymphoma. J Nucl Med. 2001;42:1139–43.
Fong Y, Saldinger PF, Akhurst T, et al. Utility of 18-F FDG positron emission tomography scanning on selection of patients for resection of hepatic colorectal metastases. Am J Surg. 1999;178:282–7.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Mukherji, A. (2018). Taking a Decision and Ordering Investigations. In: Basics of Planning and Management of Patients during Radiation Therapy. Springer, Singapore. https://doi.org/10.1007/978-981-10-6659-7_1
Download citation
DOI: https://doi.org/10.1007/978-981-10-6659-7_1
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-6658-0
Online ISBN: 978-981-10-6659-7
eBook Packages: MedicineMedicine (R0)