Biotechnology of Commercial Microbial Products

  • Sushma Chityala
  • Vidhyadhar Nandana
  • Dharanidaran Jayachandran
  • Ashish A. Prabhu
  • Veeranki Venkata DasuEmail author


Industrial biotechnology has revolutionized the conventional manufacturing of chemicals through engineering of microbes, especially in recent years largely owing to reengineering of cellular metabolism. Metabolic engineering has been widely used to overproduce indigenously synthesized metabolites in E. coli, S. cerevisiae, and other hosts. Plant secondary metabolites are low molecular weight compounds which not only help the plant in its defense mechanism but also are helpful to humans in curing a wide variety of ailments/diseases. The amount of secondary metabolite production is very less using traditional techniques, in comparison with conventional methods where they are produced in large quantities from different microbes using metabolic and cellular engineering. In this chapter, we have focused on various plant secondary metabolites produced through metabolic engineering from microbes such as E. coli and S. cerevisiae.


Plant secondary metabolites Metabolic engineering E. coli S. cerevisiae Flavonoids 



The authors would like to acknowledge the Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati for providing facilities for successful completion of this book chapter.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  • Sushma Chityala
    • 1
  • Vidhyadhar Nandana
    • 1
    • 2
  • Dharanidaran Jayachandran
    • 1
  • Ashish A. Prabhu
    • 1
  • Veeranki Venkata Dasu
    • 1
    Email author
  1. 1.Biochemical Engineering Laboratory, Department of Biosciences and BioengineeringIndian Institute of Technology (IIT) GuwahatiGuwahatiIndia
  2. 2.Institute of Chemistry and Biochemistry, Freie UniversitatBerlinGermany

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