Abstract
Molecular imprinting is a technology for the synthesis of tailor-made recognition materials by polymerization of suitable functional monomers in the presence of desired template. As a result, smart polymers with high specificity and selectivity are obtained. Hydrogels are defined as insoluble polymeric networks produced from hydrophilic polymer chains with capability to absorb water and preserve their shape without dissolving. The imprinting of hydrogels is more complicated comparing to rigid structure. However, the exponential increase in fabrication of imprinted hydrogels is observed. The novel, advanced applications in pharmacy and medicine are explored including areas such as drug delivery systems or sensors in different analytical methods utilized in diagnostics. In this chapter, a brief overview of hydrogel imprinting process together with various synthetic approaches is discussed followed by detailed description of possible applications of imprinted hydrogels in pharmaceutical and biomedical sciences. Finally, some current limits and future prospects for the imprinted hydrogels are pointed out.
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Sobiech, M., LuliĆski, P. (2018). Imprinted Polymeric Gels for Pharmaceutical and Biomedical Purposes. In: Thakur, V., Thakur, M., Voicu, S. (eds) Polymer Gels. Gels Horizons: From Science to Smart Materials. Springer, Singapore. https://doi.org/10.1007/978-981-10-6080-9_7
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