Optimal ISA-PID-Based Drug Concentration Control in Cancer Chemotherapy

  • Pandey Vivek
  • Pachauri Nikhil
  • Rani Asha
  • Singh Vijander
Conference paper
Part of the Advances in Intelligent Systems and Computing book series (AISC, volume 624)


The aim of this work is to design an efficient controller for optimum scheduling of drug during cancer treatment. The conceptual design of ISA-PID controller is applied for this purpose, and its parametric values are optimized by applying the cuckoo search algorithm (CSA) which results to the CSA-ISAPID controller. The simulated annealing (SA) and genetic algorithm (GA) are also used for comparative study. Simulation results reveal that CSA-ISAPID is able to control drug concentration more precisely in comparison with other designed controllers with minimum overshoot and settling time. Further results demonstrate that reduction in cancerous cells is high for CSA-ISAPID.


Cancer chemotherapy ISA-PID Genetic algorithm (GA) Simulated annealing (SA) Cuckoo search algorithm (CSA) 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Pandey Vivek
    • 1
  • Pachauri Nikhil
    • 1
  • Rani Asha
    • 1
  • Singh Vijander
    • 1
  1. 1.Instrumentation and Control Engineering DivisionNSITNew DelhiIndia

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