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Marine Sponge-Associated Microbiome: Reservoir of Novel Bioactive Compounds

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Mining of Microbial Wealth and MetaGenomics

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Abstract

Oceans consist of around half a million to ten million species out of which sponges, being the oldest and almost omnipresent of the marine metazoans, make an integral part of marine benthic biodiversity and play an important role in benthic–pelagic coupling. Sponges are the most popular invertebrate microbial hosts of today. A symbiotic relationship between the two is predicted. Sponge-associated microbes in league with the sponges themselves are believed to produce a large array of bioactive compounds. However, the true origin of most of these compounds is still ambiguous and remains a key issue in further developmental stages of biotechnological applications. Also most of the microorganisms associated with marine sponges remain so far uncultivable. Today, with advances in the molecular biology techniques, nearly complete microbial diversity can be accessed for understanding diversity and abundance within the microbiome, and functional screening approaches based on homology-based screening give further insights into the specific traits which may be useful in the discovery of novel natural products.

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Acknowledgements

The authors are thankful to the RGSTC—Maharashtra Gene Bank Programme and the entire team; NCMR-NCCS, Pune; and IISER, Pune, for the funding and support provided. The authors also wish to thank Mr. Chinmay S. Kulkarni for the underwater photographs and Ms. Neha Shintre for the photographs shared.

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  1. Indian Institute of Science Education and Research, Pune, India

    Uttara Lele-Rahalkar

  2. National Centre for Microbial Resource, National Centre for Cell Science, Central Tower, Sai Trinity Building Garware Circle, Sutarwadi, Pashan Pune, Maharashtra, 411 021, India

    Shrikant Pawar

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Correspondence to Shrikant Pawar .

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  1. Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, New Delhi, India

    Vipin Chandra Kalia

  2. Microbial Culture Collection, National Centre for Cell Science, Pune, India

    Yogesh Shouche

  3. Environmental Biotechnology and Genomics Division, National Environmental Engineering Research Institute (CSIR), Nagpur, India

    Hemant J. Purohit

  4. Microbial Culture Collection, National Centre for Cell Science, Pune, India

    Praveen Rahi

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© 2017 Springer Nature Singapore Pte Ltd.

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Lele-Rahalkar, U., Pawar, S. (2017). Marine Sponge-Associated Microbiome: Reservoir of Novel Bioactive Compounds. In: Kalia, V., Shouche, Y., Purohit, H., Rahi, P. (eds) Mining of Microbial Wealth and MetaGenomics. Springer, Singapore. https://doi.org/10.1007/978-981-10-5708-3_11

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