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Histopathology

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Management of Urothelial Carcinoma

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Abstract

There are numerous benign and malignant tumors occurring in the bladder. Epithelial metaplasia, leukoplakia, inverted papilloma, papilloma, nephrogenic adenoma, cystitis cystica, and leiomyoma are common conditions of benign tumor in the bladder. Inverted papilloma is histologically defined as inverted growth pattern of normal urothelial cell. Behavior of inverted papilloma shows benign feature with 1% incidence of tumor recurrence and not related to urothelial carcinoma; transurethral resection of the tumor is the treatment of choice. Urothelial papilloma was considered as Ta grade 1 malignant tumor before 1998, when the World Health Organization (WHO) changed bladder cancer classification. Nephrogenic adenoma is a rare condition caused by chronic irritation of urothelium. Cystitis cystica and cystitis glandularis commonly affect the normal bladder and are also associated with chronic inflammatory condition. Leiomyoma occurs most commonly in childbearing-aged women, and if patient complains of severe pain, surgical removal of tumor is needed.

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Authors and Affiliations

  1. Department of Urology, Seoul National University Hospital, Seoul, South Korea

    Jungyo Suh

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  1. Jungyo Suh
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Editors and Affiliations

  1. Department of Urology, Seoul National University Hospital, Seoul, Korea (Republic of)

    Ja Hyeon Ku

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© 2019 Springer Nature Singapore Pte Ltd.

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Suh, J. (2019). Histopathology. In: Ku, J. (eds) Management of Urothelial Carcinoma. Springer, Singapore. https://doi.org/10.1007/978-981-10-5502-7_2

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  • DOI: https://doi.org/10.1007/978-981-10-5502-7_2

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  • Print ISBN: 978-981-10-5501-0

  • Online ISBN: 978-981-10-5502-7

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