Nondrug Treatment for Refractory Status Epilepticus

  • Guoming Luan
  • Xuefeng WangEmail author


Although various drugs, such as benzodiazepines, anesthetics, and intravenous antiepileptic drugs (AEDs), are used to control refractory status epilepticus (RSE), many cases of RSE are not effectively controlled. In such cases, efforts to control RSE may take the form of nonpharmacological measures, including therapeutic hypothermia, electroconvulsive therapy, neuromodulatory treatment, and the implementation of a ketogenic diet. These measures are not widely used in RSE, but studies have shown that they can play a role in controlling RSE. In this chapter, we summarize the efficacy, safety, and application of these treatments.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2017

Authors and Affiliations

  1. 1.Beijing Key Laboratory of Epilepsy, Department of Neurology, Center of Epilepsy, Beijing Institute for Brain DisordersSanbo Brain Hospital Capital Medical UniversityBeijingChina
  2. 2.Chongqing Key Laboratory of Neurology, Department of NeurologyThe First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

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