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Introduction

  • Bin Zhuang
Chapter
  • 240 Downloads
Part of the Springer Theses book series (Springer Theses)

Abstract

The tradition classic approach toward genetic approach is present. Several methods for DNA extraction, amplification and electrophoresis are enumerated. Different kinds of approaches have their own advantages and application occasions. Microfluidic is a newly developed technology that aims at precisely manipulating fluidic of micro-scale. The microfluidic made it possible to integrate tradition genetic analysis process onto one single microchip for automation. Several trials have been made to transplant tradition process onto microfluidic platform, although various weak points restricted them from further industrialization. This chapter will give a brief introduction of the standard three-step process of genetic analysis on each step followed by a detailed expatiation on the development of microfluidic technology. All steps of genetic analysis, extraction, amplification and detection, have all been transplanted on-chip separately, and further researches also reported the integration of partial process. Several integrated systems are also introduced, along with careful evaluations. At the end of chapter, the significance of this study will be stated, and mainlines of following chapters will be addressed.

Keywords

Microfluidic Platform Dimethylpolysiloxane (PDMS) Mathies Group Paper Chip Forensic Human Identification 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Bin Zhuang
    • 1
  1. 1.National Engineering Research Center for Beijing Biochip TechnologyCapitalbio CorporationBeijingChina

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