Abstract
Breastfeeding provides significant advantage to both mother and child. There are many inflammatory dermatoses which can present exclusively over breast and nipple area or can present in generalized form during this period. These dermatoses could be the cause of cessation of breastfeeding in mother. Topical corticosteroid is the mainstay of therapy in such dermatosis. The advantage that topical corticosteroids offer should not be denied to the patient because of fear of their side effects. Using less potent steroid and that too on smaller area can reduce the risk to both mother and breastfed infant.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Katz M, Gans EH. Topical corticosteroids, structure-activity and the glucocorticoid receptor: discovery and development—a process of “planned serendipity”. J Pharm Sci. 2008;97:2936–47.
Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, editors. Fitzpatcrik’s dermatology in general medicine. 7th ed. New York, NY: McGraw-Hill; 2006.
Lagos BR, Maibach HI. Topical corticosteroids: unapproved uses, dosages, or indications. Clin Dermatol. 2002;20:490–2.
Tauscher AE, Fleischer AB Jr, Phelps KC, Feldman SR. Psoriasis and pregnancy. J Cutan Med Surg. 2002;6:561–70.
Hardman JG, Limbird LE, Gilman AG. Goodman and Gilman’s the pharmacologic basis of therapeutics. 7th ed. New York, NY: McGraw-Hill; 1985. p. 1473.
Schaefer H, Zesch A, Stuttgen G. Penetration, permeation, and absorption of triamcinolone acetonide in normal and psoriatic skin. Arch Dermatol Res. 1977;258:241–9.
Turpeinen M. Absorption of hydrocortisone from the skin reservoir in atopic dermatitis. Br J Dermatol. 1991;124:358–60.
Barnetson RS, White AD. The use of corticosteroids in dermatological practice. Med J Aust. 1992;156:428–31.
Melendres JL, Bucks DA, Camel E, Wester RC, Maibach HI. In vivo percutaneous absorption of hydrocortisone: multiple-application dosing in man. Pharm Res. 1992;9:1164–7.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in pregnancy and lactation. 8th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008.
Greenberger PA, Odeh YK, Frederiksen MC, Atkinson AJ Jr. Pharmacokinetics of prednisolone transfer to breast milk. Clin Pharmacol Ther. 1993;53:324–8.
Barrett ME, Heller MM, Fullerton Stone H, Murase JE. Dermatoses of the breast in lactation. Dermatol Ther. 2013;26:331–6.
Noti A, Grob K, Biedermann M. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38(3):317–25.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer Nature Singapore Pte Ltd.
About this chapter
Cite this chapter
Mittal, A., Mehta, S. (2018). Pros and Cons of Topical Corticosteroids in Lactating Females. In: Lahiri, K. (eds) A Treatise on Topical Corticosteroids in Dermatology. Springer, Singapore. https://doi.org/10.1007/978-981-10-4609-4_7
Download citation
DOI: https://doi.org/10.1007/978-981-10-4609-4_7
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-4608-7
Online ISBN: 978-981-10-4609-4
eBook Packages: MedicineMedicine (R0)